ID   C8-D1A
AC   CVCL_6379
SY   C8D1A; Astrocyte type I clone
DR   CLO; CLO_0002155
DR   ATCC; CRL-2541
DR   CCRID; 4201MOU-CCTCC00177
DR   CCTCC; GDC0177
DR   CLS; 300316
DR   PRIDE; PXD000501
DR   PRIDE; PXD001597
DR   Wikidata; Q54808244
RX   PubMed=6466977;
RX   PubMed=24753479;
RX   PubMed=26227174;
RX   PubMed=32561641;
CC   Characteristics: Susceptible to infection by mouse scrapie prion (PrPSc) strains 22L and RML (PubMed=32561641).
CC   Omics: Deep proteome analysis.
CC   Omics: Secretome proteome analysis.
CC   Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
CC   Cell type: Astrocyte of cerebellum; CL=CL_0002603.
CC   Breed/subspecies: C57BL/6.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   8D
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 13
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RX   PubMed=6466977; DOI=10.1016/0006-8993(84)90377-9;
RA   Alliot F., Pessac B.;
RT   "Astrocytic cell clones derived from established cultures of 8-day
RT   postnatal mouse cerebella.";
RL   Brain Res. 306:283-291(1984).
//
RX   PubMed=24753479; DOI=10.1002/pmic.201300495;
RA   Han D.-H., Jin J.-H., Woo J.-M., Min H., Kim Y.-S.;
RT   "Proteomic analysis of mouse astrocytes and their secretome by a
RT   combination of FASP and StageTip-based, high pH, reversed-phase
RT   fractionation.";
RL   Proteomics 14:1604-1609(2014).
//
RX   PubMed=26227174; DOI=10.1002/pmic.201400623;
RA   Woo J.-M., Han D.-H., Park J.-H., Kim S.-J., Kim Y.-S.;
RT   "In-depth characterization of the secretome of mouse CNS cell lines by
RT   LC-MS/MS without prefractionation.";
RL   Proteomics 15:3617-3622(2015).
//
RX   PubMed=32561641; DOI=10.1074/jbc.RA120.012596; PMCID=PMC7450132;
RA   Tahir W., Abdulrahman B., Abdelaziz D.H.A., Thapa S., Walia R.,
RA   Schatzl H.M.;
RT   "An astrocyte cell line that differentially propagates murine
RT   prions.";
RL   J. Biol. Chem. 295:11572-11583(2020).
//