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Cellosaurus 5/9 m a3-18 (CVCL_6358)

[Text version]
Cell line name 5/9 m a3-18
Synonyms 5/9 M alpha 3-18; 5/9 ma3-18 (0.2); CHO 5/9 M alpha3-18; CHO-3ACSF-69
Accession CVCL_6358
Resource Identification Initiative To cite this cell line use: 5/9 m a3-18 (RRID:CVCL_6358)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-10154.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2432; CSF1.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=3493529; DOI=10.1126/science.3493529
Wong G.G., Temple P.A., Leary A.C., Witek-Giannotti J.S., Yang Y.-C., Brennan A., Chung M., Murtha P., Kriz R., Kaufman R.J., Ferenz C.R., Sibley B.S., Turner K.J., Hewick R.M., Clark S.C., Yanai N., Yokota H., Yamada M., Saito M., Motoyoshi K., Takaku F.
Human CSF-1: molecular cloning and expression of 4-kb cDNA encoding the human urinary protein.
Science 235:1504-1508(1987)

Patent=US4868119
Clark S.C., Wong G.G.
Hematopoietic growth factors.
Patent number US4868119, 19-Sep-1989

Patent=US5573763
Clark S.C., Wong G.G.
Family of CSF-L proteins.
Patent number US5573763, 12-Nov-1996

Cross-references
Cell line collections (Providers) ATCC; CRL-10154
BCRC; 60185
Cell line databases/resources CLO; CLO_0001403
Encyclopedic resources Wikidata; Q54603667
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number15