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Cellosaurus Akata 3F2 (CVCL_6249)

[Text version]
Cell line name Akata 3F2
Synonyms 3F2
Accession CVCL_6249
Resource Identification Initiative To cite this cell line use: Akata 3F2 (RRID:CVCL_6249)
Comments Population: Japanese.
Virology: EBV-negative. Treated with hydroxyurea which completely eliminated EBV episomes.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro190Leufs*57 (c.569delC); ClinVar=VCV000825904; Zygosity=Unspecified (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0148 (Akata)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=9593003; DOI=10.1086/515290
Chodosh J., Holder V.P., Gan Y.-J., Belgaumi A., Sample J.T., Sixbey J.W.
Eradication of latent Epstein-Barr virus by hydroxyurea alters the growth-transformed cell phenotype.
J. Infect. Dis. 177:1194-1201(1998)

PubMed=10022853; DOI=10.1128/mcb.19.3.1651; PMCID=PMC83959
Ruf I.K., Rhyne P.W., Yang H., Borza C.M., Hutt-Fletcher L.M., Cleveland J.L., Sample J.T.
Epstein-Barr virus regulates c-MYC, apoptosis, and tumorigenicity in Burkitt lymphoma.
Mol. Cell. Biol. 19:1651-1660(1999)

Cross-references
Encyclopedic resources Wikidata; Q54749085
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18