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Cellosaurus SK-RC-48 (CVCL_6195)

[Text version]
Cell line name SK-RC-48
Synonyms SK RC 48; SKRC48
Accession CVCL_6195
Resource Identification Initiative To cite this cell line use: SK-RC-48 (RRID:CVCL_6195)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Miscellaneous: STR profile and age/sex of donor from MSKCC antibody and bioresource core facility.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:12687; VHL; Simple; p.Leu135Tyrfs*24 (c.404delT); Zygosity=Unspecified (PubMed=7915601).
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 73Y
Category Cancer cell line
STR profile Source(s): MSKCC

Markers:
AmelogeninX
CSF1PO12,13
D2S133820
D3S135817
D5S81812
D7S8209,12
D8S117911,13
D13S31713
D16S53911
D18S5114
D19S43312,16
D21S1128,30
FGA20
TH016,7
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Web pages https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-rc-p-primary-human-renal-cell-carcinoma-rcc-cell-line-collection
Publications

PubMed=2386958
Ebert T., Bander N.H., Finstad C.L., Ramsawak R.D., Old L.J.
Establishment and characterization of human renal cancer and normal kidney cell lines.
Cancer Res. 50:5531-5536(1990)

PubMed=7915601; DOI=10.1038/ng0594-85
Gnarra J.R., Tory K., Weng Y.-K., Schmidt L.S., Wei M.H., Li H., Latif F., Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.-S.R., Florence C., Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H., Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B., Linehan W.M.
Mutations of the VHL tumour suppressor gene in renal carcinoma.
Nat. Genet. 7:85-90(1994)

Cross-references
Encyclopedic resources Wikidata; Q54954595
Polymorphism and mutation databases Cosmic; 972919
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22