ID   SK-RC-31
AC   CVCL_6186
SY   SK-RC 31; SK RC 31; SKRC-31; SKRC31
DR   cancercelllines; CVCL_6186
DR   Cell_Model_Passport; SIDM01839
DR   DepMap; ACH-001194
DR   GEO; GSM374463
DR   PharmacoDB; SKRC31_1413_2019
DR   Progenetix; CVCL_6186
DR   Wikidata; Q54954573
RX   PubMed=2386958;
RX   PubMed=25984343;
RX   PubMed=27993170;
RX   PubMed=30894373;
RX   PubMed=31068700;
WW   https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-rc-m-metastatic-human-renal-cell-carcinoma-rcc-cell-line-collection
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Population: Caucasian.
CC   Doubling time: 120 hours (PubMed=25984343).
CC   Genome ancestry: African=3.19%; Native American=0.01%; East Asian, North=7.38%; East Asian, South=0%; South Asian=3.18%; European, North=19.72%; European, South=66.52% (PubMed=30894373).
CC   Miscellaneous: STR profile and sex of donor from MSKCC antibody and bioresource core facility.
CC   Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
ST   Source(s): MSKCC
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 9,11
ST   D16S539: 10,12
ST   D18S51: 20
ST   D19S433: 13,14
ST   D21S11: 29
ST   D2S1338: 23
ST   D3S1358: 17
ST   D5S818: 11,13
ST   D7S820: 8,13
ST   D8S1179: 12,16
ST   FGA: 24
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 16,17
DI   NCIt; C9385; Renal cell carcinoma
DI   ORDO; Orphanet_217071; Renal cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 24
//
RX   PubMed=2386958;
RA   Ebert T., Bander N.H., Finstad C.L., Ramsawak R.D., Old L.J.;
RT   "Establishment and characterization of human renal cancer and normal
RT   kidney cell lines.";
RL   Cancer Res. 50:5531-5536(1990).
//
RX   PubMed=25984343; DOI=10.1038/sdata.2014.35;
RA   Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S.,
RA   East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H.,
RA   Jiang G.-Z., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M.,
RA   Harrington W., Gelfand E.T., Green T.M., Tomko M.J., Gopal S.,
RA   Wong T.C., Li H.-B., Howell S., Stransky N., Liefeld T., Jang D.,
RA   Bistline J., Meyers B.H., Armstrong S.A., Anderson K.C.,
RA   Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P.,
RA   Golub T.R., Root D.E., Hahn W.C.;
RT   "Parallel genome-scale loss of function screens in 216 cancer cell
RT   lines for the identification of context-specific genetic
RT   dependencies.";
RL   Sci. Data 1:140035-140035(2014).
//
RX   PubMed=27993170; DOI=10.1186/s12943-016-0565-8;
RA   Brodaczewska K.K., Szczylik C., Fiedorowicz M., Porta C.,
RA   Czarnecka A.M.;
RT   "Choosing the right cell line for renal cell cancer research.";
RL   Mol. Cancer 15:83.1-83.15(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//