ID   SK-RC-28
AC   CVCL_6184
SY   SK RC 28; SKRC28
DR   Cosmic; 972918
DR   Wikidata; Q54954564
RX   PubMed=2386958;
RX   PubMed=6582512;
RX   PubMed=6864164;
RX   PubMed=6946460;
RX   PubMed=7915601;
WW   https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-rc-p-primary-human-renal-cell-carcinoma-rcc-cell-line-collection
CC   From: Memorial Sloan Kettering Cancer Center; New York; USA.
CC   Sequence variation: Mutation; HGNC; HGNC:12687; VHL; Simple; p.Pro86His (c.257C>A); Zygosity=Unspecified (PubMed=7915601).
CC   Miscellaneous: STR profile and age/sex of donor from MSKCC antibody and bioresource core facility.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
ST   Source(s): MSKCC
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 11,14
ST   D16S539: 12
ST   D18S51: 15
ST   D19S433: 14,15.2
ST   D21S11: 28,29
ST   D2S1338: 17,24
ST   D3S1358: 15
ST   D5S818: 10,11
ST   D7S820: 10,11
ST   D8S1179: 12,13,14
ST   FGA: 22,23
ST   TH01: 6,10
ST   TPOX: 8,10
ST   vWA: 17,18
DI   NCIt; C9385; Renal cell carcinoma
DI   ORDO; Orphanet_217071; Renal cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   51Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 23
//
RX   PubMed=2386958;
RA   Ebert T., Bander N.H., Finstad C.L., Ramsawak R.D., Old L.J.;
RT   "Establishment and characterization of human renal cancer and normal
RT   kidney cell lines.";
RL   Cancer Res. 50:5531-5536(1990).
//
RX   PubMed=6582512; DOI=10.1073/pnas.81.2.568; PMCID=PMC344720;
RA   Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.;
RT   "Cell surface antigens of human ovarian and endometrial carcinoma
RT   defined by mouse monoclonal antibodies.";
RL   Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984).
//
RX   PubMed=6864164; DOI=10.1084/jem.158.1.53; PMCID=PMC2187084;
RA   Houghton A.N., Brooks H., Cote R.J., Taormina M.C., Oettgen H.F.,
RA   Old L.J.;
RT   "Detection of cell surface and intracellular antigens by human
RT   monoclonal antibodies. Hybrid cell lines derived from lymphocytes of
RT   patients with malignant melanoma.";
RL   J. Exp. Med. 158:53-65(1983).
//
RX   PubMed=6946460; DOI=10.1073/pnas.78.8.5122; PMCID=PMC320345;
RA   Ueda R., Ogata S.-i., Morrissey D.M., Finstad C.L., Szkudlarek J.,
RA   Whitmore W.F. Jr., Oettgen H.F., Lloyd K.O., Old L.J.;
RT   "Cell surface antigens of human renal cancer defined by mouse
RT   monoclonal antibodies: identification of tissue-specific kidney
RT   glycoproteins.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:5122-5126(1981).
//
RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y.-K., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.-S.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//