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Cellosaurus SK-MEL-199 (CVCL_6104)

[Text version]
Cell line name SK-MEL-199
Synonyms SK-Mel-199; SKMEL-199; SK-MEL-199A; SK-MEL-199 (adhesion); SK-MEL-199S; SK-MEL-199 (suspension)
Accession CVCL_6104
Resource Identification Initiative To cite this cell line use: SK-MEL-199 (RRID:CVCL_6104)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=21725359; DOI=10.1038/onc.2011.250; PMCID=PMC3267014
Xing F., Persaud Y., Pratilas C.A., Taylor B.S., Janakiraman M., She Q.-B., Gallardo H.F., Liu C., Merghoub T., Hefter B.E., Dolgalev I., Viale A.J., Heguy A., de Stanchina E., Cobrinik D., Bollag G., Wolchok J.D., Houghton A.N., Solit D.B.
Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF.
Oncogene 31:446-457(2012)

PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625; PMCID=PMC4005042
Nissan M.H., Pratilas C.A., Jones A.M., Ramirez R., Won H., Liu C.-L., Tiwari S., Kong L., Hanrahan A.J., Yao Z., Merghoub T., Ribas A., Chapman P.B., Yaeger R.D., Taylor B.S., Schultz N., Berger M.F., Rosen N., Solit D.B.
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.
Cancer Res. 74:2340-2350(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6104
Encyclopedic resources Wikidata; Q54953904
Gene expression databases GEO; GSM784529
GEO; GSM784530
Polymorphism and mutation databases Cosmic; 1669192
Cosmic; 1669193
Progenetix; CVCL_6104
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number19