Cellosaurus cell line UCW 181 (CVCL

Cross-references
Cell line name	UCW 181
Accession	CVCL_5U01
Resource Identification Initiative	To cite this cell line use: UCW 181 (RRID:CVCL_5U01)
Comments	Selected for resistance to: ChEBI; CHEBI:4781; Emetine. Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG). Derived from site: In situ; Lung; UBERON=UBERON_0002048. Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations	Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line). Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy	Parent: CVCL_5U00 (UCW 124)
Sex of cell	Male
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=7444715; DOI=10.1007/BF01539152 Wasmuth J.J., Hill J.M., Vock L.S. Biochemical and genetic evidence for a new class of emetine-resistant Chinese hamster cells with alterations in the protein biosynthetic machinery. Somatic Cell Genet. 6:495-516(1980) PubMed=6965094; DOI=10.1128/mcb.1.1.58-65.1981; PMCID=PMC369327 Wasmuth J.J., Hill J.M., Vock L.S. Identification and characterization of a third complementation group of emetine-resistant Chinese hamster cell mutants. Mol. Cell. Biol. 1:58-65(1981)
Encyclopedic resources	Wikidata; Q54990098
Entry history
Entry creation	23-Feb-2016
Last entry update	29-Jun-2023
Version number	9