| Cell line name |
B02/GFP.2 |
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| Accession |
CVCL_5T77 |
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| Resource Identification Initiative |
To cite this cell line use: B02/GFP.2 (RRID:CVCL_5T77) |
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| Comments |
Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. |
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| Sequence variations |
- Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
- Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Breast adenocarcinoma (NCIt: C5214) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_5T76 (MDA-MB-231/B02) |
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| Sex of cell |
Female |
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| Age at sampling |
51Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=11697798; DOI=10.1359/jbmr.2001.16.11.2027
Peyruchaud O., Winding B., Pecheur I., Serre C.-M., Delmas P., Clezardin P.
Early detection of bone metastases in a murine model using fluorescent human breast cancer cells: application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions.
J. Bone Miner. Res. 16:2027-2034(2001) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_5T77
|
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| Encyclopedic resources |
Wikidata; Q54752256
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| Entry history |
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| Entry creation | 23-Feb-2016 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 19 |
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