ID   CHME-5
AC   CVCL_5J53
SY   CHME5
DR   Wikidata; Q54812518
RX   PubMed=7478261;
RX   PubMed=8845742;
RX   PubMed=10074188;
RX   PubMed=17157319;
RX   PubMed=30200996;
CC   Virology: Supports the replication of M-tropic HIV-1 strain YU-2 (PubMed=17157319).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Miscellaneous: The cell line name was not assigned in the original paper (PubMed=7478261).
CC   Derived from site: In situ; Fetal brain; UBERON=UBERON_0006238.
CC   Cell type: Microglial cell; CL=CL_0000129.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   8-10FW
CA   Transformed cell line
DT   Created: 14-12-15; Last updated: 10-09-24; Version: 16
//
RX   PubMed=7478261; DOI=10.1016/0304-3940(94)11792-H;
RA   Janabi N., Peudenier S., Heron B., Ng K.H., Tardieu M.;
RT   "Establishment of human microglial cell lines after transfection of
RT   primary cultures of embryonic microglial cells with the SV40 large T
RT   antigen.";
RL   Neurosci. Lett. 195:105-108(1995).
//
RX   PubMed=8845742; DOI=10.1016/0197-0186(95)00023-2;
RA   Atanassov C.L., Muller C.D., Dumont S., Rebel G., Poindron P.,
RA   Seiler N.;
RT   "Effect of ammonia on endocytosis and cytokine production by
RT   immortalized human microglia and astroglia cells.";
RL   Neurochem. Int. 27:417-424(1995).
//
RX   PubMed=10074188; DOI=10.1128/JVI.73.4.3338-3350.1999; PMCID=PMC104098;
RA   Arbour N., Cote G., Lachance C., Tardieu M., Cashman N.R.,
RA   Talbot P.J.;
RT   "Acute and persistent infection of human neural cell lines by human
RT   coronavirus OC43.";
RL   J. Virol. 73:3338-3350(1999).
//
RX   PubMed=17157319; DOI=10.1016/j.jmb.2006.11.011; PMCID=PMC7127718;
RA   Chugh P., Fan S.-S., Planelles V., Maggirwar S.B., Dewhurst S., Kim B.;
RT   "Infection of human immunodeficiency virus and intracellular viral Tat
RT   protein exert a pro-survival effect in a human microglial cell line.";
RL   J. Mol. Biol. 366:67-81(2007).
//
RX   PubMed=30200996; DOI=10.1186/s12974-018-1288-0; PMCID=PMC6131758;
RA   Dello Russo C., Cappoli N., Coletta I., Mezzogori D., Paciello F.,
RA   Pozzoli G., Navarra P., Battaglia A.;
RT   "The human microglial HMC3 cell line: where do we stand? A systematic
RT   literature review.";
RL   J. Neuroinflammation 15:259.1-259.24(2018).
//