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Cellosaurus LNCaP-luc-M6 (CVCL_5J30)

[Text version]
Cell line name LNCaP-luc-M6
Accession CVCL_5J30
Resource Identification Initiative To cite this cell line use: LNCaP-luc-M6 (RRID:CVCL_5J30)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Discontinued: Revvity/PerkinElmer; 119271; true.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1379 (LNCaP clone FGC)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=15042605; DOI=10.1002/pros.20003
Caroline D. Scatena, Mischa A. Hepner, Yoko A. Oei, Joan M. Dusich, Shang-Fan Yu, Tony Purchio, Pamela R. Contag, Darlene E. Jenkins;
Imaging of bioluminescent LNCaP-luc-M6 tumors: a new animal model for the study of metastatic human prostate cancer.
Prostate 59:292-303(2004)

Cross-references
Cell line collections (Providers) Revvity/PerkinElmer; 119271
Cell line databases/resources cancercelllines; CVCL_5J30
Encyclopedic resources Wikidata; Q54902842
Entry history
Entry creation14-Dec-2015
Last entry update14-Aug-2025
Version number15