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Cellosaurus BxPc-3-luc2 (CVCL_5J14)

[Text version]
Cell line name BxPc-3-luc2
Synonyms BxPc3-luc2
Accession CVCL_5J14
Resource Identification Initiative To cite this cell line use: BxPc-3-luc2 (RRID:CVCL_5J14)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 6770; SMAD4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val487_Pro492delinsAla (c.1460_1474delGTGTAGGTGCTGTCA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; None_reported; -; Zygosity=- (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0186 (BxPC-3)
Sex of cell Female
Age at sampling 61Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) PerkinElmer; 125058 - Discontinued
Cell line databases/resources cancercelllines; CVCL_5J14
Encyclopedic resources Wikidata; Q54798762
Entry history
Entry creation14-Dec-2015
Last entry update10-Sep-2024
Version number16