Cellosaurus cell line SH-SY5Y-HFE C282Y (CVCL

Cross-references
Cell line name	SH-SY5Y-HFE C282Y
Accession	CVCL_5I53
Resource Identification Initiative	To cite this cell line use: SH-SY5Y-HFE C282Y (RRID:CVCL_5I53)
Comments	Population: Caucasian. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4886; HFE (Note=With p.Cys282Tyr (c.845G>A) and a FLAG tag). Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
Disease	Neuroblastoma (NCIt: C3270) Neuroblastoma (ORDO: Orphanet_635)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0019 (SH-SY5Y)
Sex of cell	Female
Age at sampling	4Y
Category	Cancer cell line
Publications	PubMed=17194693; DOI=10.1096/fj.06-6397com Lee S.Y., Patton S.M., Henderson R.J., Connor J.R. Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE. FASEB J. 21:564-576(2007)
Cell line collections (Providers)	Kerafast; EQ1003
Cell line databases/resources	cancercelllines; CVCL_5I53
Encyclopedic resources	Wikidata; Q54953226
Entry history
Entry creation	14-Dec-2015
Last entry update	19-Dec-2024
Version number	15