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Cellosaurus NaV 1.3 KIR 2.1 (CVCL_5I44)

[Text version]
Cell line name NaV 1.3 KIR 2.1
Synonyms Spiking HEK cells
Accession CVCL_5I44
Resource Identification Initiative To cite this cell line use: NaV 1.3 KIR 2.1 (RRID:CVCL_5I44)
Comments Characteristics: Generate spontaneous electrical action potentials (PubMed=24391999).
Genetic integration: Method=Transfection/transduction; Gene=RGD; 3635; Scn3a.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:104744; Kcnj2.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5I43 (HEK293-Nav 1.3)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
STR profile Source(s): ATCC=CRL-3269

Markers:
AmelogeninX
CSF1PO12
D5S8188
D7S82011,12
D13S31712,14
D16S5399,13
TH017,9.3
TPOX11
vWA16,19

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Publications

PubMed=24391999; DOI=10.1371/journal.pone.0085221; PMCID=PMC3877367
Park J., Werley C.A., Venkatachalam V., Kralj J.M., Dib-Hajj S.D., Waxman S.G., Cohen A.E.
Screening fluorescent voltage indicators with spontaneously spiking HEK cells.
PLoS ONE 8:E85221-E85221(2013)

Cross-references
Cell line collections (Providers) ATCC; CRL-3269 - Discontinued
Encyclopedic resources Wikidata; Q54907499
Entry history
Entry creation14-Dec-2015
Last entry update10-Sep-2024
Version number12