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Cellosaurus COSB (CVCL_5I33)

[Text version]
Cell line name COSB
Accession CVCL_5I33
Resource Identification Initiative To cite this cell line use: COSB (RRID:CVCL_5I33)
Sequence variations
  • Mutation; VGNC; VGNC:84862; EP300; Simple; p.Asn1570fs (c.4704dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; VGNC; VGNC:44555; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); Zygosity=Homozygous (from parent cell line).
  • Mutation; VGNC; VGNC:47719; TP53; Simple; p.Ala150fs (c.447delG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; VGNC; VGNC:47719; TP53; Simple; p.Leu184Phe (c.550C>T); Zygosity=Heterozygous (from parent cell line).
Disease Canine hemangiosarcoma (NCIt: C122783)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: German Shepherd; VBO=VBO_0200577.
Hierarchy Parent: CVCL_0C95 (SB-HSA)
Sex of cell Male
Age at sampling 9Y
Category Cancer cell line
Publications

PubMed=24582862; DOI=10.1016/j.yexcr.2014.02.020; PMCID=PMC4256199
Kim J.-H., Frantz A.M., Anderson K.L., Graef A.J., Scott M.C., Robinson S., Sharkey L.C., O'Brien T.D., Dickerson E.B., Modiano J.F.
Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment.
Exp. Cell Res. 323:155-164(2014)

Cross-references
Encyclopedic resources Wikidata; Q54814331
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number8