| Cell line name |
U-251MG AgCl1 |
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| Synonyms |
U-251 MG AgCl1; U-251 MGAgCl1 |
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| Accession |
CVCL_5G63 |
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| Resource Identification Initiative |
To cite this cell line use: U-251MG AgCl1 (RRID:CVCL_5G63) |
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| Comments |
Population: Caucasian.
Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872. |
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| Sequence variations |
- Mutation; HGNC; 9588; PTEN; Simple; p.Glu242Valfs*15 (c.723_724dupTG); ClinVar=VCV000536553; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
|
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| Disease |
Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0021 (U-251MG) |
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| Sex of cell |
Male |
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| Age at sampling |
75Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=2454731
Nister M., Libermann T.A., Betsholtz C., Pettersson M., Claesson-Welsh L., Heldin C.-H., Schlessinger J., Westermark B.
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.
Cancer Res. 48:3910-3918(1988) DOI=10.1016/B978-0-12-333530-2.50005-8
Nister M., Westermark B.
Human glioma cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.17-42; Academic Press; New York; USA (1994) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_5G63
|
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| Encyclopedic resources |
Wikidata; Q54973553
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| Entry history |
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| Entry creation | 14-Dec-2015 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 13 |
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