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Cellosaurus GEN2.2 (CVCL_5G44)

[Text version]
Cell line name GEN2.2
Synonyms Gen2.2; GEN 2.2; Gen 2.2; HLA-A*0201+ pDC line
Accession CVCL_5G44
Resource Identification Initiative To cite this cell line use: GEN2.2 (RRID:CVCL_5G44)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-2938.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Plasmacytoid dendritic cell; CL=CL_0000784.
Disease Blastic plasmacytoid dendritic cell neoplasm (NCIt: C7203)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5G45 ! GEN3
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
Web pages https://web.archive.org/web/20160706131224/http://www.clg.niigata-u.ac.jp:80/~matak/eng/resmat12.pdf
Publications

PubMed=16365416; DOI=10.4049/jimmunol.176.1.248
Chaperot L., Blum A., Manches O., Lui G., Angel J., Molens J.-P., Plumas J.
Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells.
J. Immunol. 176:248-255(2006)

Patent=US7341870
Plumas J., Chaperot L.
Dendritic cell line.
Patent number US7341870, 11-Mar-2008

PubMed=22696054; DOI=10.1038/jid.2012.152
Aspord C., Leccia M.-T., Salameire D., Laurin D., Chaperot L., Charles J., Plumas J.
HLA-A(*)0201(+) plasmacytoid dendritic cells provide a cell-based immunotherapy for melanoma patients.
J. Invest. Dermatol. 132:2395-2406(2012)

Cross-references
Encyclopedic resources Wikidata; Q54835560
Entry history
Entry creation14-Dec-2015
Last entry update29-Jun-2023
Version number8