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Cellosaurus Y1-Kin-2 (CVCL_5G21)

[Text version]
Cell line name Y1-Kin-2
Synonyms Kin-2; Kin 2
Accession CVCL_5G21
Resource Identification Initiative To cite this cell line use: Y1-Kin-2 (RRID:CVCL_5G21)
Comments Selected for resistance to: ChEBI; CHEBI:64211; 8-bromo-3',5'-cyclic AMP (8-bromoadenosine 3',5'-cyclic monophosphate; 8-Br-cAMP).
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Mouse adrenal cortical carcinoma (NCIt: C22992)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: LAF1.
Hierarchy Parent: CVCL_W154 (Y1-BS1)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=221910; DOI=10.1073/pnas.76.4.1896; PMCID=PMC383499
Rae P.A., Gutmann N.S., Tsao J., Schimmer B.P.
Mutations in cyclic AMP-dependent protein kinase and corticotropin (ACTH)-sensitive adenylate cyclase affect adrenal steroidogenesis.
Proc. Natl. Acad. Sci. U.S.A. 76:1896-1900(1979)

PubMed=6270152; DOI=10.1016/S0021-9258(19)68600-X
Watt V.M., Schimmer B.P.
Association of a 68,000-dalton protein with adrenocorticotropin-sensitive adenylate cyclase activity in Y1 adrenocortical tumor cells.
J. Biol. Chem. 256:11365-11371(1981)

PubMed=8388994; DOI=10.1210/mend.7.4.8388994
Olson M.F., Krolczyk A.J., Gorman K.B., Steinberg R.A., Schimmer B.P.
Molecular basis for the 3',5'-cyclic adenosine monophosphate resistance of Kin mutant Y1 adrenocortical tumor cells.
Mol. Endocrinol. 7:477-487(1993)

PubMed=15541570; DOI=10.1016/j.mce.2003.12.020
Rainey W.E., Saner K., Schimmer B.P.
Adrenocortical cell lines.
Mol. Cell. Endocrinol. 228:23-38(2004)

Cross-references
Encyclopedic resources Wikidata; Q54995186
Entry history
Entry creation14-Dec-2015
Last entry update29-Jun-2023
Version number6