ID   hTERT-RPE1 mRuby-APC15
AC   CVCL_5F68
SY   hTERT-RPE1/APC15; hTERT-RPE1 APC15
DR   CancerTools; 151710
DR   Wikidata; Q54896634
DR   Ximbio; 151710
RX   PubMed=21926987;
CC   Characteristics: Tetracycline-inducible expression of APC15-IRES2-mRuby.
CC   Genetic integration: Method=Transfection; Gene=FPbase; 8MJ78; mRuby2 (Note=Bright red fluorescent protein derived from eqFP61).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:24531; ANAPC15.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
CC   Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_VP32 ! hTERT-RPE1 FRT/TR
SX   Female
AG   1Y
CA   Telomerase immortalized cell line
DT   Created: 14-12-15; Last updated: 10-04-25; Version: 15
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RX   PubMed=21926987; DOI=10.1038/ncb2347; PMCID=PMC3188299;
RA   Mansfeld J., Collin P., Collins M.O., Choudhary J.S., Pines J.;
RT   "APC15 drives the turnover of MCC-CDC20 to make the spindle assembly
RT   checkpoint responsive to kinetochore attachment.";
RL   Nat. Cell Biol. 13:1234-1243(2011).
//