ID   V79/E36
AC   CVCL_5A58
SY   E36; E-36; E36,HGPRT-
DR   KCB; KCB 87014YJ
DR   Wikidata; Q54992615
RX   PubMed=3049611;
RX   PubMed=4345996;
RX   PubMed=6752155;
CC   Selected for resistance to: ChEBI; CHEBI:63486; 8-azaguanine.
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Misspelling: CHO-E36; Note=Incorrect as not a CHO derivative but a V79 derivative.
CC   Misspelling: CHO E36; Note=Incorrect as not a CHO derivative but a V79 derivative.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_5A61 ! V79 A3
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 14-12-15; Last updated: 29-06-23; Version: 12
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RX   PubMed=3049611; DOI=10.1016/S0021-9258(19)37648-3;
RA   Kulka R.G., Raboy B., Schuster R., Parag H.A., Diamond G.,
RA   Ciechanover A., Marcus M.;
RT   "A Chinese hamster cell cycle mutant arrested at G2 phase has a
RT   temperature-sensitive ubiquitin-activating enzyme, E1.";
RL   J. Biol. Chem. 263:15726-15731(1988).
//
RX   PubMed=4345996; DOI=10.1093/genetics/72.2.239; PMCID=PMC1212824;
RA   Gillin F.D., Roufa D.J., Beaudet A.L., Caskey C.T.;
RT   "8-azaguanine resistance in mammalian cells. I. Hypoxanthine-guanine
RT   phosphoribosyltransferase.";
RL   Genetics 72:239-252(1972).
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RX   PubMed=6752155; DOI=10.1002/jcp.1041130125;
RA   Hirschberg J., Marcus M.;
RT   "Isolation by a replica-plating technique of Chinese hamster
RT   temperature-sensitive cell cycle mutants.";
RL   J. Cell. Physiol. 113:159-166(1982).
//