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Cellosaurus CHO-DXB11 F435 (CVCL_5A31)

[Text version]
Cell line name CHO-DXB11 F435
Synonyms F435
Accession CVCL_5A31
Resource Identification Initiative To cite this cell line use: CHO-DXB11 F435 (RRID:CVCL_5A31)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3546; F8 (Note=Construct called N8 with 20-769 and 1657-2351).
Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Omics: Genome sequenced.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=19906157; DOI=10.1111/j.1365-2516.2009.02135.x
Thim L., Vandahl B.S., Karlsson J., Klausen N.K., Pedersen J., Krogh T.N., Kjalke M., Petersen J.M., Johnsen L.B., Bolt G., Norby P.L., Steenstrup T.D.
Purification and characterization of a new recombinant factor VIII (N8).
Haemophilia 16:349-359(2010)

PubMed=25887056; DOI=10.1186/s12864-015-1391-x; PMCID=PMC4359788
Kaas C.S., Kristensen C., Betenbaugh M.J., Andersen M.R.
Sequencing the CHO DXB11 genome reveals regional variations in genomic stability and haploidy.
BMC Genomics 16:160.1-160.9(2015)

Cross-references
Encyclopedic resources Wikidata; Q54833139
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number10