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Cellosaurus 4-HS-MYC (CVCL_5A28)

[Text version]
Cell line name 4-HS-MYC
Synonyms 4 HS MYC
Accession CVCL_5A28
Resource Identification Initiative To cite this cell line use: 4-HS-MYC (RRID:CVCL_5A28)
Comments Characteristics: Expression of mouse Myc is under the control of a Drosophila hsp70 promoter. Contains ~900 copies of the Myc gene (PubMed=3526329).
Genetic integration: Method=Transfection; Gene=MGI; MGI:97250; Myc.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=3526329; DOI=10.1073/pnas.83.15.5414; PMCID=PMC386297
Wurm F.M., Gwinn-Hardy K.A., Kingston R.E.
Inducible overproduction of the mouse c-myc protein in mammalian cells.
Proc. Natl. Acad. Sci. U.S.A. 83:5414-5418(1986)

Patent=EP0232845A2
Kingston R.E., Wurm F.M.
Inducible heat shock and amplification system.
Patent number EP0232845A2, 19-Aug-1987

Cross-references
Encyclopedic resources Wikidata; Q54602850
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number9