• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro151His (c.452C>A); ClinVar=VCV000376639; Zygosity=Unspecified (PubMed=7503188; PubMed=9887230).
  

PubMed=1777413; DOI=10.1002/gcc.2870030604
Worsham M.J., Van Dyke D.L., Grenman S.E., Grenman R., Hopkins M.P., Roberts J.A., Gasser K.M., Schwartz D.R., Carey T.E.
Consistent chromosome abnormalities in squamous cell carcinoma of the vulva.
Genes Chromosomes Cancer 3:420-432(1991)

PubMed=1958593; DOI=10.1002/gcc.2870030406
Bradford C.R., Kimmel K.A., Van Dyke D.L., Worsham M.J., Tilley B.J., Burk D., del Rosario F., Lutz S., Tooley R., Hayashida D.J.S., Carey T.E.
11p deletions and breakpoints in squamous cell carcinoma: association with altered reactivity with the UM-E7 antibody.
Genes Chromosomes Cancer 3:272-282(1991)

PubMed=7503188; DOI=10.1016/0002-9378(95)90636-3
Hietanen S.H., Kurvinen K., Syrjanen K.J., Grenman S.E., Carey T.E., McClatchey K.D., Syrjanen S.M.
Mutation of tumor suppressor gene p53 is frequently found in vulvar carcinoma cells.
Am. J. Obstet. Gynecol. 173:1477-1482(1995)

PubMed=7599042; DOI=10.1038/bjc.1995.289; PMCID=PMC2034151
Hietanen S.H., Grenman S.E., Syrjanen K.J., Lappalainen K., Kauppinen J., Carey T.E., Syrjanen S.M.
Human papillomavirus in vulvar and vaginal carcinoma cell lines.
Br. J. Cancer 72:134-139(1995)

PubMed=8646696; DOI=10.1002/(SICI)1097-0142(19960501)77:9<1940::AID-CNCR26>3.0.CO;2-Z
Jaakkola M., Rantanen V., Grenman S.E., Kulmala J., Grenman R.
In vitro concurrent paclitaxel and radiation of four vulvar squamous cell carcinoma cell lines.
Cancer 77:1940-1946(1996)

PubMed=9887230; DOI=10.1006/gyno.1998.5194
Rantanen V., Grenman S.E., Kurvinen K., Hietanen S.H., Raitanen M., Syrjanen S.M.
p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines.
Gynecol. Oncol. 71:352-358(1998)

PubMed=15047230; DOI=10.1016/j.ygyno.2003.12.033
Raitanen M., Worsham M.J., Lakkala T., Carey T.E., Van Dyke D.L., Grenman R., Klemi P., Rantanen V., Isola J.J., Grenman S.E.
Characterization of 10 vulvar carcinoma cell lines by karyotyping, comparative genomic hybridization and flow cytometry.
Gynecol. Oncol. 93:155-163(2004)

PubMed=31654625; DOI=10.1016/j.yexcr.2019.111684
Dongre H.N., Rana N., Fromreide S., Rajthala S., Boe Engelsen I., Paradis J., Gutkind J.S., Vintermyr O.K., Johannessen A.C., Bjorge L., Costea D.E.
Establishment of a novel cancer cell line derived from vulvar carcinoma associated with lichen sclerosus exhibiting a fibroblast-dependent tumorigenic potential.
Exp. Cell Res. 386:111684.1-111684.9(2020)