Cellosaurus cell line AMC-HN-6 (CVCL

Cross-references
Cell line name	AMC-HN-6
Synonyms	Amc-HN-6; AMC-HN6; Asian Medical Center-Head and Neck cancer-6
Accession	CVCL_5964
Resource Identification Initiative	To cite this cell line use: AMC-HN-6 (RRID:CVCL_5964)
Comments	Population: Korean. Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (PubMed=24336076).
Disease	Floor of mouth squamous cell carcinoma (NCIt: C4041) Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	61Y
Category	Cancer cell line
Publications	PubMed=9349880; DOI=10.3109/00016489709113477 Kim S.Y., Chu K.-C., Lee H.R., Lee K.-S., Carey T.E. Establishment and characterization of nine new head and neck cancer cell lines. Acta Oto-Laryngol. 117:775-784(1997) PubMed=24336076; DOI=10.1038/cddis.2013.488; PMCID=PMC3877559 Roh J.-L., Kim E.H., Park H.B., Park J.Y. The Hsp90 inhibitor 17-(allylamino)-17-demethoxygeldanamycin increases cisplatin antitumor activity by inducing p53-mediated apoptosis in head and neck cancer. Cell Death Dis. 4:e956.1-e956.8(2013)
Cell line databases/resources	cancercelllines; CVCL_5964
Encyclopedic resources	Wikidata; Q54749717
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	18