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Cellosaurus K-562R (CVCL_5950)

[Text version]
Cell line name K-562R
Synonyms K562R; K562-R
Accession CVCL_5950
Resource Identification Initiative To cite this cell line use: K-562R (RRID:CVCL_5950)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:45783; Imatinib (Gleevec; STI571).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Cross-references
Anatomy/cell type resources BTO; BTO:0004462
Chemistry resources ChEMBL-Cells; CHEMBL4295438
ChEMBL-Targets; CHEMBL4296447
PubChem_Cell_line; CVCL_5950
Encyclopedic resources Wikidata; Q54899222
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number22