ID   PDV
AC   CVCL_5858
DR   CLS; 400314
DR   Wikidata; Q54946870
RX   PubMed=102384;
RX   PubMed=1855225;
RX   PubMed=1934268;
RX   PubMed=2185890;
RX   PubMed=2414007;
RX   PubMed=6190961;
RX   PubMed=12807763;
CC   Transformant: ChEBI; CHEBI:254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
CC   Breed/subspecies: C57BL/10 LP.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   <1D
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 13
//
RX   PubMed=102384;
RA   Fusenig N.E., Amer S.M., Boukamp P., Worst P.K.M.;
RT   "Characteristics of chemically transformed mouse epidermal cells in
RT   vitro and in vivo.";
RL   Bull. Cancer 65:271-279(1978).
//
RX   PubMed=1855225;
RA   Buchmann A., Ruggeri B., Klein-Szanto A.J.P., Balmain A.;
RT   "Progression of squamous carcinoma cells to spindle carcinomas of
RT   mouse skin is associated with an imbalance of H-ras alleles on
RT   chromosome 7.";
RL   Cancer Res. 51:4097-4101(1991).
//
RX   PubMed=1934268; DOI=10.1093/carcin/12.10.1875;
RA   Quintanilla M., Haddow S., Jonas D., Jaffe D.R., Bowden G.T.,
RA   Balmain A.;
RT   "Comparison of ras activation during epidermal carcinogenesis in vitro
RT   and in vivo.";
RL   Carcinogenesis 12:1875-1881(1991).
//
RX   PubMed=2185890; DOI=10.1016/0092-8674(90)90523-H;
RA   Bremner R., Balmain A.;
RT   "Genetic changes in skin tumor progression: correlation between
RT   presence of a mutant ras gene and loss of heterozygosity on mouse
RT   chromosome 7.";
RL   Cell 61:407-417(1990).
//
RX   PubMed=2414007;
RA   Fusenig N.E., Dzarlieva-Petrusevska R.T., Breitkreutz D.;
RT   "Phenotypic and cytogenetic characteristics of different stages during
RT   spontaneous transformation of mouse keratinocytes in vitro.";
RL   Carcinog. Compr. Surv. 9:293-326(1985).
//
RX   PubMed=6190961; DOI=10.1111/1523-1747.ep12541032;
RA   Fusenig N.E., Breitkreutz D., Dzarlieva-Petrusevska R.T., Boukamp P.,
RA   Bohnert A., Tilgen W.;
RT   "Growth and differentiation characteristics of transformed
RT   keratinocytes from mouse and human skin in vitro and in vivo.";
RL   J. Invest. Dermatol. 81:168s-175s(1983).
//
RX   PubMed=12807763; DOI=10.1093/carcin/bgg067;
RA   Zoumpourlis V., Solakidi S., Papathoma A., Papaevangeliou D.;
RT   "Alterations in signal transduction pathways implicated in tumour
RT   progression during multistage mouse skin carcinogenesis.";
RL   Carcinogenesis 24:1159-1165(2003).
//