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Cellosaurus FAMPAC (CVCL_5749)

[Text version]
Cell line name FAMPAC
Synonyms FamPAC; Fampac; PA-CLS-13; PA-CLS 13
Accession CVCL_5749
Resource Identification Initiative To cite this cell line use: FAMPAC (RRID:CVCL_5749)
Comments Population: Caucasian.
Doubling time: 24-48 hours (PubMed=15112280).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
HLA typing Source: CLS=300309
Class I
HLA-AA*03:01:01
HLA-BB*27:05:01
HLA-CC*15:02:01
Class II
HLA-DPDPB1*03.01:01
HLA-DQDQA1*05:05:01
DQB1*03:01:01
HLA-DRDRB1*12:01:01
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Hereditary pancreatic carcinoma (NCIt: C43298)
Familial pancreatic carcinoma (ORDO: Orphanet_1333)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_5750 (FAMPAC-A)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
STR profile Source(s): CLS=300309

Markers:
AmelogeninX
CSF1PO10
D3S135816,17
D5S81810,11
D7S82011
D13S3178
D16S53914
D18S5115
D21S1132.2
Penta D11
Penta E12,13
vWA15

Run an STR similarity search on this cell line
Publications

PubMed=15112280; DOI=10.1002/cncr.20193
Eisold S., Ryschich E., Linnebacher M., Giese T., Nauheimer D., Wild A., Bartsch D.K., Buchler M.W., Schmidt J.
Characterization of FAMPAC, a newly identified human pancreatic carcinoma cell line with a hereditary background.
Cancer 100:1978-1986(2004)

DOI=10.22029/jlupub-12385
Oberlin L.
Treatment of pancreatic carcinoma cell lines in vitro and vivo with a monoclonal antibody against the transferrin receptor.
Thesis VMD (2009); Justus-Liebig-Universitat Giessen; Giessen; Germany

PubMed=22753594; DOI=10.1158/1078-0432.CCR-12-0827; PMCID=PMC3513499
Cui Y.-F., Brosnan-Cashman J.A., Blackford A.L., Sur S., Hruban R.H., Kinzler K.W., Vogelstein B., Maitra A., Diaz L.A. Jr., Iacobuzio-Donahue C.A., Eshleman J.R.
Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity.
Clin. Cancer Res. 18:6519-6530(2012)

DOI=10.4172/2324-9293.1000104
Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D.
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

Cross-references
Cell line collections (Providers) CLS; 300309
Cell line databases/resources cancercelllines; CVCL_5749
Encyclopedic resources Wikidata; Q54833235
Polymorphism and mutation databases Cosmic; 2664044
IARC_TP53; 20736
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number22