ID   NB-1691
AC   CVCL_5628
SY   NB1691; NB 1691
DR   BTO; BTO_0002834
DR   GEO; GSM2371244
DR   GEO; GSM2394384
DR   IARC_TP53; 23604
DR   Wikidata; Q54907502
RX   PubMed=9802058;
RX   PubMed=9815701;
RX   PubMed=10933967;
RX   PubMed=11306486;
RX   PubMed=28350380;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=9802058).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by RNAseq.
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   1-3Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 12
//
RX   PubMed=9802058;
RA   McPake C.R., Tillman D.M., Poquette C.A., George E.O., Houghton J.A.,
RA   Harris L.C.;
RT   "Bax is an important determinant of chemosensitivity in pediatric
RT   tumor cell lines independent of Bcl-2 expression and p53 status.";
RL   Oncol. Res. 10:235-244(1998).
//
RX   PubMed=9815701;
RA   Thompson J., Zamboni W.C., Cheshire P.J., Lutz L., Luo X.-L., Li Y.-L.,
RA   Houghton J.A., Stewart C.F., Houghton P.J.;
RT   "Efficacy of systemic administration of irinotecan against
RT   neuroblastoma xenografts.";
RL   Clin. Cancer Res. 3:423-431(1997).
//
RX   PubMed=10933967; DOI=10.1006/mthe.2000.0064;
RA   Pawlik C.A., Iyengar R.V., Krull E.J., Mason S.E., Khanna R.,
RA   Harris L.C., Potter P.M., Danks M.K., Guichard S.M.;
RT   "Use of the ornithine decarboxylase promoter to achieve N-MYC-mediated
RT   overexpression of a rabbit carboxylesterase to sensitize neuroblastoma
RT   cells to CPT-11.";
RL   Mol. Ther. 1:457-463(2000).
//
RX   PubMed=11306486;
RA   Iyengar R.V., Pawlik C.A., Krull E.J., Phelps D.A., Burger R.A.,
RA   Harris L.C., Potter P.M., Danks M.K.;
RT   "Use of a modified ornithine decarboxylase promoter to achieve
RT   efficient c-MYC- or N-MYC-regulated protein expression.";
RL   Cancer Res. 61:3045-3052(2001).
//
RX   PubMed=28350380; DOI=10.1038/sdata.2017.33; PMCID=PMC5369315;
RA   Harenza J.L., Diamond M.A., Adams R.N., Song M.M., Davidson H.L.,
RA   Hart L.S., Dent M.H., Fortina P., Reynolds C.P., Maris J.M.;
RT   "Transcriptomic profiling of 39 commonly-used neuroblastoma cell
RT   lines.";
RL   Sci. Data 4:170033-170033(2017).
//