ID   KYM-1D4
AC   CVCL_5616
DR   Wikidata; Q54900788
RX   PubMed=1960402;
RX   PubMed=10485267;
CC   Problematic cell line: Possibly misclassified. It is not certain that the parent cell line originate from a alveolar rhabdomyosarcoma (ARMS). It lacks the PAXA3-FOXO1 gene fusion characteristics of ARMS. Many papers classify it as an embryonal rhabdomyosarcoma (ERMS) and we accordingly describe it as such.
CC   Population: Japanese.
CC   Sequence variation: Gene deletion; HGNC; 11103; SMARCB1; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Neck; UBERON=UBERON_0000974.
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3007 ! KYM-1
SX   Male
AG   9M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 18
RX   PubMed=1960402; DOI=10.1016/0022-1759(91)90239-C;
RA   Meager A.;
RT   "A cytotoxicity assay for tumour necrosis factor using a human
RT   rhabdomyosarcoma cell line.";
RL   J. Immunol. Methods 144:141-143(1991).
RX   PubMed=10485267; DOI=10.1016/S0022-1759(99)00081-2;
RA   Meager A.;
RT   "A tumour necrosis factor-alpha (TNF-alpha) sensitive adherent KYM-1D4
RT   derived cell line: use in TNF-alpha cytotoxicity assays in the
RT   presence of actinomycin D.";
RL   J. Immunol. Methods 227:197-198(1999).