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Cellosaurus OPCT-2 (CVCL_5570)

[Text version]
Cell line name OPCT-2
Synonyms OPCT 2; OPCT2
Accession CVCL_5570
Resource Identification Initiative To cite this cell line use: OPCT-2 (RRID:CVCL_5570)
Comments Doubling time: 1.8 +- 0.2 days (CelloPub=CLPUB00396).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5567 ! OPCN-2
Sex of cell Male
Age at sampling 58Y
Category Transformed cell line
Web pages https://bioivt.com/opc-prostate-and-normal-cell-lines/
Publications

CLPUB00396
Eliason J.F., Theocharous P., Palazzolo B.C., Mehmood A.
Derivation and initial characterization of three new prostate cancer cell lines and three new immortalized normal prostate epithelial cell lines.
Proc. Am. Assoc. Cancer Res. 45:792-792(2004)

CLPUB00242
Palazzolo B.C., Heng H.H.-Q., Mohammad R.M., Theocharous P., Eliason J.F.
Characterization of three pairs of prostate cells lines derived from tumor and adjacent normal tissues.
Proc. Am. Assoc. Cancer Res. 46:1974-1974(2005)

PubMed=28094783; DOI=10.1038/srep40633; PMCID=PMC5240554
Harner-Foreman N., Vadakekolathu J., Laversin S.A., Mathieu M.G., Reeder S., Pockley A.G., Rees R.C., Boocock D.J.
A novel spontaneous model of epithelial-mesenchymal transition (EMT) using a primary prostate cancer derived cell line demonstrating distinct stem-like characteristics.
Sci. Rep. 7:40633-40633(2017)

Cross-references
Encyclopedic resources Wikidata; Q54936472
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number19