ID   OPCT-1
AC   CVCL_5569
SY   OPCT 1; OPCT1
DR   Wikidata; Q54936467
RX   CelloPub=CLPUB00242;
RX   CelloPub=CLPUB00396;
RX   PubMed=28094783;
WW   https://bioivt.com/opc-prostate-and-normal-cell-lines/
CC   Doubling time: 1.1 +- 0.02 days (CelloPub=CLPUB00396).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_5566 ! OPCN-1
SX   Male
AG   68Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 19
//
RX   CelloPub=CLPUB00242;
RA   Palazzolo B.C., Heng H.H.-Q., Mohammad R.M., Theocharous P.,
RA   Eliason J.F.;
RT   "Characterization of three pairs of prostate cells lines derived from
RT   tumor and adjacent normal tissues.";
RL   Proc. Am. Assoc. Cancer Res. 46:1974-1974(2005).
//
RX   CelloPub=CLPUB00396;
RA   Eliason J.F., Theocharous P., Palazzolo B.C., Mehmood A.;
RT   "Derivation and initial characterization of three new prostate cancer
RT   cell lines and three new immortalized normal prostate epithelial cell
RT   lines.";
RL   Proc. Am. Assoc. Cancer Res. 45:792-792(2004).
//
RX   PubMed=28094783; DOI=10.1038/srep40633; PMCID=PMC5240554;
RA   Harner-Foreman N., Vadakekolathu J., Laversin S.A., Mathieu M.G.,
RA   Reeder S., Pockley A.G., Rees R.C., Boocock D.J.;
RT   "A novel spontaneous model of epithelial-mesenchymal transition (EMT)
RT   using a primary prostate cancer derived cell line demonstrating
RT   distinct stem-like characteristics.";
RL   Sci. Rep. 7:40633-40633(2017).
//