ID   IOSE-80
AC   CVCL_5546
SY   IOSE 80; IOSE80; NFHIOSE-80; IOSE80UBC; IOSE-Van; IOSE-VAN
DR   Lonza; 13
DR   Wikidata; Q54897904
RX   DOI=10.5282/edoc.3898;
RX   PubMed=1326894;
RX   PubMed=7967506;
RX   PubMed=10329039;
RX   PubMed=15706405;
RX   PubMed=15947112;
RX   PubMed=19926575;
RX   PubMed=23415752;
CC   From: Canadian Ovarian Tissue Bank, University of British Columbia; Vancouver; Canada.
CC   Doubling time: 26.2 hours (PubMed=10329039).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 17
//
RX   DOI=10.5282/edoc.3898;
RA   Euer N.I.;
RT   "Identification of target genes for the therapy and diagnosis of
RT   ovarian carcinoma.";
RL   Thesis PhD (2005); Ludwig Maximilians University of Munich; Munich; Germany.
//
RX   PubMed=1326894; DOI=10.1016/S0002-9378(11)91579-8;
RA   Maines-Bandiera S.L., Kruk P.A., Auersperg N.;
RT   "Simian virus 40-transformed human ovarian surface epithelial cells
RT   escape normal growth controls but retain morphogenetic responses to
RT   extracellular matrix.";
RL   Am. J. Obstet. Gynecol. 167:729-735(1992).
//
RX   PubMed=7967506;
RA   Auersperg N., Maines-Bandiera S.L., Dyck H.G., Kruk P.A.;
RT   "Characterization of cultured human ovarian surface epithelial cells:
RT   phenotypic plasticity and premalignant changes.";
RL   Lab. Invest. 71:510-518(1994).
//
RX   PubMed=10329039; DOI=10.1006/gyno.1999.5348;
RA   Kruk P.A., Godwin A.K., Hamilton T.C., Auersperg N.;
RT   "Telomeric instability and reduced proliferative potential in ovarian
RT   surface epithelial cells from women with a family history of ovarian
RT   cancer.";
RL   Gynecol. Oncol. 73:229-236(1999).
//
RX   PubMed=15706405; DOI=10.3892/or.13.3.375;
RA   Euer N.I., Kaul S., Deissler H., Mobus V.J., Zeillinger R.,
RA   Weidle U.H.;
RT   "Identification of L1CAM, Jagged2 and neuromedin U as ovarian
RT   cancer-associated antigens.";
RL   Oncol. Rep. 13:375-387(2005).
//
RX   PubMed=15947112; DOI=10.1677/erc.1.00896;
RA   Choi J.-H., Choi K.-C., Auersperg N., Leung P.C.K.;
RT   "Gonadotropins upregulate the epidermal growth factor receptor through
RT   activation of mitogen-activated protein kinases and
RT   phosphatidyl-inositol-3-kinase in human ovarian surface epithelial
RT   cells.";
RL   Endocr. Relat. Cancer 12:407-421(2005).
//
RX   PubMed=19926575; DOI=10.1309/AJCPTK87EMMIKPFS; PMCID=PMC3040237;
RA   DeRycke M.S., Andersen J.D., Harrington K.M., Pambuccian S.E.,
RA   Kalloger S.E., Boylan K.L.M., Argenta P.A., Skubitz A.P.N.;
RT   "S100A1 expression in ovarian and endometrial endometrioid carcinomas
RT   is a prognostic indicator of relapse-free survival.";
RL   Am. J. Clin. Pathol. 132:846-856(2009).
//
RX   PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007; PMCID=PMC4106023;
RA   Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S.,
RA   Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G.,
RA   Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J.,
RA   Mills G.B., Hennessy B.T.;
RT   "BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one
RT   functionally deleterious BRCA1 mutation.";
RL   Mol. Oncol. 7:567-579(2013).
//