ID   IOSE-29
AC   CVCL_5535
SY   IOSE 29; IOSE29; NFHIOSE-29; IOSE-Mar; IOSE-MAR
DR   BTO; BTO:0004132
DR   IARC_TP53; 28486
DR   Wikidata; Q54897886
RX   PubMed=1326894;
RX   PubMed=7967506;
RX   PubMed=10329039;
RX   PubMed=10339573;
RX   PubMed=19926575;
RX   PubMed=20204287;
RX   PubMed=23415752;
CC   From: Canadian Ovarian Tissue Bank, University of British Columbia; Vancouver; Canada.
CC   Doubling time: 33.7 hours (PubMed=10329039).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Omics: Array-based CGH.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 19
//
RX   PubMed=1326894; DOI=10.1016/S0002-9378(11)91579-8;
RA   Maines-Bandiera S.L., Kruk P.A., Auersperg N.;
RT   "Simian virus 40-transformed human ovarian surface epithelial cells
RT   escape normal growth controls but retain morphogenetic responses to
RT   extracellular matrix.";
RL   Am. J. Obstet. Gynecol. 167:729-735(1992).
//
RX   PubMed=7967506;
RA   Auersperg N., Maines-Bandiera S.L., Dyck H.G., Kruk P.A.;
RT   "Characterization of cultured human ovarian surface epithelial cells:
RT   phenotypic plasticity and premalignant changes.";
RL   Lab. Invest. 71:510-518(1994).
//
RX   PubMed=10329039; DOI=10.1006/gyno.1999.5348;
RA   Kruk P.A., Godwin A.K., Hamilton T.C., Auersperg N.;
RT   "Telomeric instability and reduced proliferative potential in ovarian
RT   surface epithelial cells from women with a family history of ovarian
RT   cancer.";
RL   Gynecol. Oncol. 73:229-236(1999).
//
RX   PubMed=10339573; DOI=10.1073/pnas.96.11.6249; PMCID=PMC26867;
RA   Auersperg N., Pan J., Grove B.D., Peterson T., Fisher J.,
RA   Maines-Bandiera S.L., Somasiri A., Roskelley C.D.;
RT   "E-cadherin induces mesenchymal-to-epithelial transition in human
RT   ovarian surface epithelium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 96:6249-6254(1999).
//
RX   PubMed=19926575; DOI=10.1309/AJCPTK87EMMIKPFS; PMCID=PMC3040237;
RA   DeRycke M.S., Andersen J.D., Harrington K.M., Pambuccian S.E.,
RA   Kalloger S.E., Boylan K.L.M., Argenta P.A., Skubitz A.P.N.;
RT   "S100A1 expression in ovarian and endometrial endometrioid carcinomas
RT   is a prognostic indicator of relapse-free survival.";
RL   Am. J. Clin. Pathol. 132:846-856(2009).
//
RX   PubMed=20204287; DOI=10.3892/or_00000728; PMCID=PMC2909445;
RA   Langland G.T., Yannone S.M., Langland R.A., Nakao A., Guan Y.-H.,
RA   Long S.B.T., Vonguyen L., Chen D.J., Gray J.W., Chen F.-Q.;
RT   "Radiosensitivity profiles from a panel of ovarian cancer cell lines
RT   exhibiting genetic alterations in p53 and disparate DNA-dependent
RT   protein kinase activities.";
RL   Oncol. Rep. 23:1021-1026(2010).
//
RX   PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007; PMCID=PMC4106023;
RA   Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S.,
RA   Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G.,
RA   Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J.,
RA   Mills G.B., Hennessy B.T.;
RT   "BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one
RT   functionally deleterious BRCA1 mutation.";
RL   Mol. Oncol. 7:567-579(2013).
//