ID   WSU-HN31
AC   CVCL_5526
SY   HN31; Wayne State University-Head and Neck 31
DR   Cosmic; 922085
DR   Cosmic; 2043893
DR   Cosmic; 2131845
DR   Cosmic; 2439754
DR   Wikidata; Q54994488
RX   PubMed=7705939;
RX   PubMed=8001221;
RX   PubMed=9389571;
RX   PubMed=21868764;
RX   PubMed=28196595;
RX   PubMed=29156801;
WW   https://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   Omics: Deep exome analysis.
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
ST   Source(s): PubMed=21868764
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 11,12
ST   D16S539: 11,12
ST   D5S818: 12,13
ST   D7S820: 10
ST   TH01: 7,9
ST   TPOX: 6,11
ST   vWA: 15,18
DI   NCIt; C102872; Pharyngeal squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_5525 ! WSU-HN30
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 19
//
RX   PubMed=7705939; DOI=10.1002/ijc.2910610117;
RA   Cardinali M., Pietraszkiewicz H., Ensley J.F., Robbins K.C.;
RT   "Tyrosine phosphorylation as a marker for aberrantly regulated
RT   growth-promoting pathways in cell lines derived from head and neck
RT   malignancies.";
RL   Int. J. Cancer 61:98-103(1995).
//
RX   PubMed=8001221; DOI=10.1093/carcin/15.12.2683;
RA   Yeudall W.A., Crawford R.Y., Ensley J.F., Robbins K.C.;
RT   "MTS1/CDK4I is altered in cell lines derived from primary and
RT   metastatic oral squamous cell carcinoma.";
RL   Carcinogenesis 15:2683-2686(1994).
//
RX   PubMed=9389571; DOI=10.1002/(SICI)1097-0215(19971114)73:4<551::AID-IJC16>3.0.CO;2-C;
RA   Patel V., Jakus J., Harris C.M., Ensley J.F., Robbins K.C.,
RA   Yeudall W.A.;
RT   "Altered expression and activity of G1/S cyclins and cyclin-dependent
RT   kinases characterize squamous cell carcinomas of the head and neck.";
RL   Int. J. Cancer 73:551-555(1997).
//
RX   PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690;
RA   Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C.,
RA   Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G.,
RA   Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.;
RT   "Assembly and initial characterization of a panel of 85 genomically
RT   validated cell lines from diverse head and neck tumor sites.";
RL   Clin. Cancer Res. 17:7248-7264(2011).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=29156801; DOI=10.18632/oncotarget.21174;
RA   Kalu N.N., Mazumdar T., Peng S.-H., Shen L., Sambandam V., Rao X.-Y.,
RA   Xi Y.-X., Li L.-R., Qi Y., Gleber-Netto F.O., Patel A., Wang J.,
RA   Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.;
RT   "Genomic characterization of human papillomavirus-positive and
RT   -negative human squamous cell cancer cell lines.";
RL   Oncotarget 8:86369-86383(2017).
//