ID   WSU-HN30
AC   CVCL_5525
SY   HN30; HN-30; Wayne State University-Head and Neck 30
DR   BTO; BTO:0005039
DR   Cosmic; 922084
DR   Cosmic; 2131844
DR   Cosmic; 2296299
DR   GEO; GSM1643583
DR   Wikidata; Q54994487
RX   PubMed=7705939;
RX   PubMed=8001221;
RX   PubMed=9049184;
RX   PubMed=9389571;
RX   PubMed=21868764;
RX   PubMed=25275298;
RX   PubMed=26754630;
RX   PubMed=28196595;
RX   PubMed=29156801;
WW   https://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   Part of: OPC-22 oral and pharyngeal cancer cell line panel.
CC   Omics: Deep exome analysis.
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): PubMed=21868764; PubMed=25275298
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 11 (PubMed=25275298)
ST   D13S317: 11,12 (PubMed=21868764)
ST   D16S539: 11,12
ST   D18S51: 13,16
ST   D21S11: 28
ST   D3S1358: 16
ST   D5S818: 12,13
ST   D7S820: 10
ST   D8S1179: 15,17
ST   FGA: 20,24
ST   Penta D: 2.2
ST   Penta E: 8,12
ST   TH01: 7,9
ST   TPOX: 6,11
ST   vWA: 15,18
DI   NCIt; C102872; Pharyngeal squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_5526 ! WSU-HN31
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 21-03-23; Version: 17
//
RX   PubMed=7705939; DOI=10.1002/ijc.2910610117;
RA   Cardinali M., Pietraszkiewicz H., Ensley J.F., Robbins K.C.;
RT   "Tyrosine phosphorylation as a marker for aberrantly regulated
RT   growth-promoting pathways in cell lines derived from head and neck
RT   malignancies.";
RL   Int. J. Cancer 61:98-103(1995).
//
RX   PubMed=8001221; DOI=10.1093/carcin/15.12.2683;
RA   Yeudall W.A., Crawford R.Y., Ensley J.F., Robbins K.C.;
RT   "MTS1/CDK4I is altered in cell lines derived from primary and
RT   metastatic oral squamous cell carcinoma.";
RL   Carcinogenesis 15:2683-2686(1994).
//
RX   PubMed=9049184; DOI=10.1002/(SICI)1098-2744(199702)18:2<89::AID-MC4>3.0.CO;2-L;
RA   Yeudall W.A., Jakus J., Ensley J.F., Robbins K.C.;
RT   "Functional characterization of p53 molecules expressed in human
RT   squamous cell carcinomas of the head and neck.";
RL   Mol. Carcinog. 18:89-96(1997).
//
RX   PubMed=9389571; DOI=10.1002/(SICI)1097-0215(19971114)73:4<551::AID-IJC16>3.0.CO;2-C;
RA   Patel V., Jakus J., Harris C.M., Ensley J.F., Robbins K.C.,
RA   Yeudall W.A.;
RT   "Altered expression and activity of G1/S cyclins and cyclin-dependent
RT   kinases characterize squamous cell carcinomas of the head and neck.";
RL   Int. J. Cancer 73:551-555(1997).
//
RX   PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690;
RA   Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C.,
RA   Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G.,
RA   Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.;
RT   "Assembly and initial characterization of a panel of 85 genomically
RT   validated cell lines from diverse head and neck tumor sites.";
RL   Clin. Cancer Res. 17:7248-7264(2011).
//
RX   PubMed=25275298; DOI=10.18632/oncotarget.2417;
RA   Martin D., Abba M.C., Molinolo A.A., Vitale-Cross L., Wang Z.-Y.,
RA   Zaida M., Delic N.C., Samuels Y., Lyons J.G., Gutkind J.S.;
RT   "The head and neck cancer cell oncogenome: a platform for the
RT   development of precision molecular therapies.";
RL   Oncotarget 5:8906-8923(2014).
//
RX   PubMed=26754630; DOI=10.1186/s13046-016-0284-4;
RA   Hyakusoku H., Sano D., Takahashi H., Hatano T., Isono Y., Shimada S.,
RA   Ito Y., Myers J.N., Oridate N.;
RT   "JunB promotes cell invasion, migration and distant metastasis of head
RT   and neck squamous cell carcinoma.";
RL   J. Exp. Clin. Cancer Res. 35:6.1-6.12(2016).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=29156801; DOI=10.18632/oncotarget.21174;
RA   Kalu N.N., Mazumdar T., Peng S.-H., Shen L., Sambandam V., Rao X.-Y.,
RA   Xi Y.-X., Li L.-R., Qi Y., Gleber-Netto F.O., Patel A., Wang J.,
RA   Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.;
RT   "Genomic characterization of human papillomavirus-positive and
RT   -negative human squamous cell cancer cell lines.";
RL   Oncotarget 8:86369-86383(2017).
//