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Cellosaurus WSU-HN12 (CVCL_5518)

[Text version]
Cell line name WSU-HN12
Synonyms HN12; HN-12; Wayne State University-Head and Neck 12
Accession CVCL_5518
Resource Identification Initiative To cite this cell line use: WSU-HN12 (RRID:CVCL_5518)
Comments Part of: OPC-22 oral and pharyngeal cancer cell line panel.
Omics: Deep exome analysis.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5515 ! WSU-HN4
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=25275298

Markers:
AmelogeninX
CSF1PO10,11
D3S135815
D5S81811,12
D7S82010
D8S117913
D13S31713
D16S5399
D18S5114
D21S1132,33.2
FGA20,26
Penta D9,10
Penta E7
TH017,9
TPOX11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=8001221; DOI=10.1093/carcin/15.12.2683
Yeudall W.A., Crawford R.Y., Ensley J.F., Robbins K.C.
MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma.
Carcinogenesis 15:2683-2686(1994)

PubMed=7705939; DOI=10.1002/ijc.2910610117
Cardinali M., Pietraszkiewicz H., Ensley J.F., Robbins K.C.
Tyrosine phosphorylation as a marker for aberrantly regulated growth-promoting pathways in cell lines derived from head and neck malignancies.
Int. J. Cancer 61:98-103(1995)

PubMed=9049184; DOI=10.1002/(SICI)1098-2744(199702)18:2<89::AID-MC4>3.0.CO;2-L
Yeudall W.A., Jakus J., Ensley J.F., Robbins K.C.
Functional characterization of p53 molecules expressed in human squamous cell carcinomas of the head and neck.
Mol. Carcinog. 18:89-96(1997)

PubMed=9389571; DOI=10.1002/(SICI)1097-0215(19971114)73:4<551::AID-IJC16>3.0.CO;2-C
Patel V., Jakus J., Harris C.M., Ensley J.F., Robbins K.C., Yeudall W.A.
Altered expression and activity of G1/S cyclins and cyclin-dependent kinases characterize squamous cell carcinomas of the head and neck.
Int. J. Cancer 73:551-555(1997)

PubMed=25275298; DOI=10.18632/oncotarget.2417; PMCID=PMC4253406
Martin D., Abba M.C., Molinolo A.A., Vitale-Cross L., Wang Z.-Y., Zaida M., Delic N.C., Samuels Y., Lyons J.G., Gutkind J.S.
The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies.
Oncotarget 5:8906-8923(2014)

Cross-references
Anatomy/cell type resources BTO; BTO_0005040
Chemistry resources ChEMBL-Cells; CHEMBL4483183
PubChem_Cell_line; CVCL_5518
Encyclopedic resources Wikidata; Q54994470
Polymorphism and mutation databases Cosmic; 922079
Cosmic; 2043897
Cosmic; 2296297
Cosmic; 2513908
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18