ID   FRSK
AC   CVCL_5501
SY   Fetal Rat Skin Keratinocytes
DR   JCRB; JCRB0005
DR   Wikidata; Q54835176
RX   PubMed=894748;
RX   PubMed=2172343;
RX   PubMed=2428814;
CC   Transformant: ChEBI; CHEBI_29865; Benzo[a]pyrene.
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
CC   Breed/subspecies: Sprague Dawley; RS=RS_0000681.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Sex unspecified
AG   Embryo
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 17
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RX   PubMed=894748; DOI=10.1093/jnci/59.3.867;
RA   Indo K., Wilson R.B.;
RT   "Fetal rat keratinizing epidermal cells in culture: effects of
RT   long-term treatment by benzo[a]pyrene on their growth
RT   characteristics.";
RL   J. Natl. Cancer Inst. 59:867-880(1977).
//
RX   PubMed=2172343; DOI=10.1111/j.1346-8138.1990.tb01676.x;
RA   Takahashi H., Tamura T., Tsutsui M., Iizuka H.;
RT   "Adenylate cyclase system in fetal rat keratinizing epidermal cells
RT   (FRSK cells) and SV40-transformed human keratinocytes.";
RL   J. Dermatol. 17:457-464(1990).
//
RX   PubMed=2428814; DOI=10.1016/S0021-9258(18)69263-4;
RA   Chida K., Kato N., Kuroki T.;
RT   "Down regulation of phorbol diester receptors by proteolytic
RT   degradation of protein kinase C in a cultured cell line of fetal rat
RT   skin keratinocytes.";
RL   J. Biol. Chem. 261:13013-13018(1986).
//