Cellosaurus logo
expasy logo

Cellosaurus VACO 10MS (CVCL_5393)

[Text version]
Cell line name VACO 10MS
Synonyms VACO10MS; Vaco10MS; V10MS; VACO-10M; VACO10M; V10M; VACO 10; VACO10
Accession CVCL_5393
Resource Identification Initiative To cite this cell line use: VACO 10MS (RRID:CVCL_5393)
Comments Part of: AstraZeneca Colorectal cell line (AZCL) panel.
Doubling time: 36 hours (PubMed=6498841).
Microsatellite instability: Stable (MSS) (PubMed=24755471).
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
Sequence variations
Disease Cecum adenocarcinoma (NCIt: C5543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5394 ! VACO 10P
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=6498841
McBain J.A., Weese J.L., Meisner L.F., Wolberg W.H., Willson J.K.V.
Establishment and characterization of human colorectal cancer cell lines.
Cancer Res. 44:5813-5821(1984)

PubMed=7761852; DOI=10.1126/science.7761852
Markowitz S.D., Wang J., Myeroff L.L., Parsons R., Sun L.-Z., Lutterbaugh J.D., Fan R.S., Zborowska E., Kinzler K.W., Vogelstein B., Brattain M.G., Willson J.K.V.
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability.
Science 268:1336-1338(1995)

PubMed=8755562; DOI=10.1073/pnas.93.15.7832; PMCID=PMC38834
Liu D.-C., Pearlman E., Diaconu E., Guo K., Mori H., Haqqi T., Markowitz S.D., Willson J.K.V., Sy M.-S.
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo.
Proc. Natl. Acad. Sci. U.S.A. 93:7832-7837(1996)

PubMed=16418264; DOI=10.1073/pnas.0510146103; PMCID=PMC1327731
Liu Y., Bodmer W.F.
Analysis of p53 mutations and their expression in 56 colorectal cancer cell lines.
Proc. Natl. Acad. Sci. U.S.A. 103:976-981(2006)

PubMed=20606684; DOI=10.1038/sj.bjc.6605780; PMCID=PMC2920028
Bracht K., Nicholls A.M., Liu Y., Bodmer W.F.
5-fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.
Br. J. Cancer 103:340-346(2010)

PubMed=23272949; DOI=10.1186/1755-8794-5-66; PMCID=PMC3543849
Schlicker A., Beran G., Chresta C.M., McWalter G., Pritchard A., Weston S., Runswick S., Davenport S., Heathcote K., Castro D.A., Orphanides G., French T., Wessels L.F.A.
Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines.
BMC Med. Genomics 5:66.1-66.15(2012)

PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013
Mouradov D., Sloggett C., Jorissen R.N., Love C.G., Li S., Burgess A.W., Arango D., Strausberg R.L., Buchanan D., Wormald S., O'Connor L., Wilding J.L., Bicknell D.C., Tomlinson I.P.M., Bodmer W.F., Mariadason J.M., Sieber O.M.
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
Cancer Res. 74:3238-3247(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_5393
ColonAtlas; VACO10
Encyclopedic resources Wikidata; Q54992654
Gene expression databases GEO; GSM784050
GEO; GSM1346859
GEO; GSM1374980
Polymorphism and mutation databases Cosmic; 948824
Cosmic; 986022
Cosmic; 1223152
Cosmic; 1312319
Cosmic; 2302023
Cosmic; 2760086
IARC_TP53; 21745
Progenetix; CVCL_5393
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number27