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Cellosaurus PMC42 (CVCL_5215)

[Text version]
Cell line name PMC42
Synonyms PMC-42; PMC 42; PMC42-ET; PMC-42 ET; PMC42ET
Accession CVCL_5215
Resource Identification Initiative To cite this cell line use: PMC42 (RRID:CVCL_5215)
Comments Part of: GrayJW breast cancer cell line panel.
Population: Caucasian.
Doubling time: 2.3 days (PubMed=6572752).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Breast carcinoma (NCIt: C4872)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_5216 (PMC42-LA)
Sex of cell Female
Age at sampling 68Y
Category Cancer cell line
STR profile Source(s): PubMed=28889351


Run an STR similarity search on this cell line
Web pages https://www.cellosaurus.org/pawefish/BreastCellLineDescriptions/pmc42.htm

PubMed=6572752; DOI=10.1093/jnci/70.4.649
Whitehead R.H., Bertoncello I., Webber L.M., Pedersen J.S.
A new human breast carcinoma cell line (PMC42) with stem cell characteristics. I. Morphologic characterization.
J. Natl. Cancer Inst. 70:649-661(1983)

PubMed=6606728; DOI=10.1093/jnci/71.6.1193
Whitehead R.H., Monaghan P., Webber L.M., Bertoncello I., Vitali A.A.
A new human breast carcinoma cell line (PMC42) with stem cell characteristics. II. Characterization of cells growing as organoids.
J. Natl. Cancer Inst. 71:1193-1203(1983)

PubMed=6381852; DOI=10.1093/jnci/73.3.643
Whitehead R.H., Quirk S.J., Vitali A.A., Funder J.W., Sutherland R.L., Murphy L.C.
A new human breast carcinoma cell line (PMC42) with stem cell characteristics. III. Hormone receptor status and responsiveness.
J. Natl. Cancer Inst. 73:643-648(1984)

PubMed=2228321; DOI=10.1002/ijc.2910460531
Monaghan P., Ormerod M.G., O'Hare M.J.
Epidermal growth factor receptors and EGF-responsiveness of the human breast-carcinoma cell line PMC42.
Int. J. Cancer 46:935-943(1990)

Leibovitz A.
Cell lines from human breast.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.161-184; Academic Press; New York (1994)

PubMed=11044355; DOI=10.1054/bjoc.2000.1458
Davidson J.M., Gorringe K.L., Chin S.-F., Orsetti B., Besret C., Courtay-Cahen C., Roberts I., Theillet C., Caldas C., Edwards P.A.W.
Molecular cytogenetic analysis of breast cancer cell lines.
Br. J. Cancer 83:1309-1317(2000)

PubMed=11161701; DOI=10.1006/excr.2000.5106
Ackland M.L., Michalczyk A., Whitehead R.H.
PMC42, a novel model for the differentiated human breast.
Exp. Cell Res. 263:14-22(2001)

Morrison B.J.
Breast cancer stem cells: tumourspheres and implications for therapy.
Thesis PhD (2010), Griffith University, Australia

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110
Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C.B., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y.-L., Mills G.B., Cho R.J., Collisson E.A., van 't Veer L.J., Spellman P.T., Gray J.W.
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

PubMed=28889351; DOI=10.1007/s10549-017-4496-x
Saunus J.M., Smart C.E., Kutasovic J.R., Johnston R.L., Kalita-de Croft P., Miranda M., Rozali E.N., Vargas A.C., Reid L.E., Lorsy E., Cocciardi S., Seidens T., McCart Reed A.E., Dalley A.J., Wockner L.F., Johnson J., Sarkar D., Askarian-Amiri M.E., Simpson P.T., Khanna K.K., Chenevix-Trench G., Al-Ejeh F., Lakhani S.R.
Multidimensional phenotyping of breast cancer cell lines to guide preclinical research.
Breast Cancer Res. Treat. 167:289-301(2018)

Cell line databases/resources cancercelllines; CVCL_5215
Chemistry resources PharmacoDB; PMC42_1275_2019
Encyclopedic resources Wikidata; Q54947618
Gene expression databases GEO; GSM217595
GEO; GSM1172988
GEO; GSM3145729
Polymorphism and mutation databases Progenetix; CVCL_5215
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number26