ID   PCI-35 [Human pancreatic adenocarcinoma]
AC   CVCL_5191
SY   PCI35
DR   BTO; BTO_0003286
DR   cancercelllines; CVCL_5191
DR   Cosmic; 707259
DR   Cosmic; 1066197
DR   Cosmic; 1644309
DR   Wikidata; Q54938693
RX   PubMed=7687590;
RX   PubMed=7804431;
RX   PubMed=8797870;
RX   PubMed=11115575;
CC   Doubling time: 33.6 hours (PubMed=7804431).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=11115575).
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 16
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RX   PubMed=7687590; DOI=10.1002/ijc.2910540618;
RA   Iwai K., Ishikura H., Kaji M., Sugiura H., Ishizu A., Takahashi C.,
RA   Kato H., Tanabe T., Yoshiki T.;
RT   "Importance of E-selectin (ELAM-1) and sialyl Lewis(a) in the adhesion
RT   of pancreatic carcinoma cells to activated endothelium.";
RL   Int. J. Cancer 54:972-977(1993).
//
RX   PubMed=7804431; DOI=10.1111/j.1440-1827.1994.tb02948.x;
RA   Sugiura H., Ishikura H., Omi M., Kaji M., Iwai K., Kishimoto T.,
RA   Takahashi T., Kimura C., Kato H., Yoshiki T.;
RT   "Lymphokine-activated killer cytotoxicity against pancreas
RT   adenocarcinoma cell lines and vascular endothelial cells.";
RL   Pathol. Int. 44:688-696(1994).
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RX   PubMed=8797870; DOI=10.1002/(SICI)1097-0215(19960822)69:4<290::AID-IJC9>3.0.CO;2-S;
RA   Kishimoto T., Ishikura H., Kimura C., Takahashi T., Kato H.,
RA   Yoshiki T.;
RT   "Phenotypes correlating to metastatic properties of pancreas
RT   adenocarcinoma in vivo: the importance of surface sialyl Lewis(a)
RT   antigen.";
RL   Int. J. Cancer 69:290-294(1996).
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RX   PubMed=11115575; DOI=10.3892/or.8.1.89;
RA   Sun C.-L., Yamato T., Furukawa T., Ohnishi Y., Kijima H., Horii A.;
RT   "Characterization of the mutations of the K-ras, p53, p16, and SMAD4
RT   genes in 15 human pancreatic cancer cell lines.";
RL   Oncol. Rep. 8:89-92(2001).
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