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Cellosaurus Y-MESO-8D (CVCL_5189)

[Text version]
Cell line name Y-MESO-8D
Accession CVCL_5189
Resource Identification Initiative To cite this cell line use: Y-MESO-8D (RRID:CVCL_5189)
Comments Population: Japanese.
Characteristics: While the primary tumor is biphasic this cell line shows sarcomatoid morphology.
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Donor information: No history of asbestos exposure (PubMed=16630136).
Misspelling: ACC-MESO-8D; IARC_TP53=24551.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
Disease Pleural sarcomatoid mesothelioma (NCIt: C45663)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_5188 ! Y-MESO-8A
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): RCB=RCB5665

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81811,12
D7S82011
D13S3178,9
D16S53912
TH017,9
TPOX11
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=16630136; DOI=10.1111/j.1349-7006.2006.00184.x; PMCID=PMC11158456
Usami N., Fukui T., Kondo M., Taniguchi T., Yokoyama T., Mori S., Yokoi K., Horio Y., Shimokata K., Sekido Y., Hida T.
Establishment and characterization of four malignant pleural mesothelioma cell lines from Japanese patients.
Cancer Sci. 97:387-394(2006)

PubMed=17270034; DOI=10.1111/j.1349-7006.2006.00386.x; PMCID=PMC11158069
Taniguchi T., Karnan S., Fukui T., Yokoyama T., Tagawa H., Yokoi K., Ueda Y., Mitsudomi T., Horio Y., Hida T., Yatabe Y., Seto M., Sekido Y.
Genomic profiling of malignant pleural mesothelioma with array-based comparative genomic hybridization shows frequent non-random chromosomal alteration regions including JUN amplification on 1p32.
Cancer Sci. 98:438-446(2007)

PubMed=21245096; DOI=10.1158/0008-5472.CAN-10-2164
Murakami H., Mizuno T., Taniguchi T., Fujii M., Ishiguro F., Fukui T., Akatsuka S., Horio Y., Hida T., Kondo Y., Toyokuni S., Osada H., Sekido Y.
LATS2 is a tumor suppressor gene of malignant mesothelioma.
Cancer Res. 71:873-883(2011)

PubMed=26011428; DOI=10.1111/cas.12698; PMCID=PMC4556387
Hakiri S., Osada H., Ishiguro F., Murakami H., Murakami-Tonami Y., Yokoi K., Sekido Y.
Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells.
Cancer Sci. 106:990-999(2015)

Cross-references
Cell line collections (Providers) RCB; RCB5665
Cell line databases/resources cancercelllines; CVCL_5189
Encyclopedic resources Wikidata; Q54995160
Gene expression databases GEO; GSM552524
GEO; GSM850287
Polymorphism and mutation databases Cosmic; 2759225
IARC_TP53; 24551
Progenetix; CVCL_5189
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21