ID   Y-MESO-28
AC   CVCL_5185
DR   cancercelllines; CVCL_5185
DR   Cosmic; 2759224
DR   GEO; GSM552534
DR   GEO; GSM850293
DR   Progenetix; CVCL_5185
DR   RCB; RCB5673
DR   Wikidata; Q54995146
RX   PubMed=19380521;
RX   PubMed=21245096;
RX   PubMed=22286761;
RX   PubMed=26011428;
CC   Population: Japanese.
CC   Sequence variation: Gene deletion; HGNC; HGNC:17795; SAV1; Zygosity=Homozygous (PubMed=21245096).
CC   Omics: Array-based CGH.
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C45662; Pleural epithelioid mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   65Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=19380521; DOI=10.1093/carcin/bgp097;
RA   Kawaguchi K., Murakami H., Taniguchi T., Fujii M., Kawata S.,
RA   Fukui T., Kondo Y., Osada H., Usami N., Yokoi K., Ueda Y., Yatabe Y.,
RA   Ito M., Horio Y., Hida T., Sekido Y.;
RT   "Combined inhibition of MET and EGFR suppresses proliferation of
RT   malignant mesothelioma cells.";
RL   Carcinogenesis 30:1097-1105(2009).
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RX   PubMed=21245096; DOI=10.1158/0008-5472.CAN-10-2164;
RA   Murakami H., Mizuno T., Taniguchi T., Fujii M., Ishiguro F., Fukui T.,
RA   Akatsuka S., Horio Y., Hida T., Kondo Y., Toyokuni S., Osada H.,
RA   Sekido Y.;
RT   "LATS2 is a tumor suppressor gene of malignant mesothelioma.";
RL   Cancer Res. 71:873-883(2011).
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RX   PubMed=22286761; DOI=10.1038/onc.2012.5;
RA   Mizuno T., Murakami H., Fujii M., Ishiguro F., Tanaka I., Kondo Y.,
RA   Akatsuka S., Toyokuni S., Yokoi K., Osada H., Sekido Y.;
RT   "YAP induces malignant mesothelioma cell proliferation by upregulating
RT   transcription of cell cycle-promoting genes.";
RL   Oncogene 31:5117-5122(2012).
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RX   PubMed=26011428; DOI=10.1111/cas.12698; PMCID=PMC4556387;
RA   Hakiri S., Osada H., Ishiguro F., Murakami H., Murakami-Tonami Y.,
RA   Yokoi K., Sekido Y.;
RT   "Functional differences between wild-type and mutant-type
RT   BRCA1-associated protein 1 tumor suppressor against malignant
RT   mesothelioma cells.";
RL   Cancer Sci. 106:990-999(2015).
//