ID   Y-MESO-26B
AC   CVCL_5183
DR   cancercelllines; CVCL_5183
DR   Cosmic; 2759228
DR   GEO; GSM552531
DR   GEO; GSM850291
DR   Progenetix; CVCL_5183
DR   RCB; RCB5671
DR   Wikidata; Q54995144
RX   PubMed=19380521;
RX   PubMed=21245096;
RX   PubMed=22286761;
RX   PubMed=26011428;
RX   PubMed=28553954;
CC   Population: Japanese.
CC   Sequence variation: Gene deletion; HGNC; HGNC:7773; NF2; Zygosity=Homozygous (PubMed=21245096).
CC   Sequence variation: Mutation; HGNC; HGNC:6515; LATS2; Simple; p.Tyr649Ter (c.1947G>C); Zygosity=Unspecified (PubMed=21245096).
CC   Omics: Array-based CGH.
CC   Omics: Transcriptome analysis by microarray.
DI   NCIt; C27779; Lymphohistiocytoid mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A1KA ! Y-MESO-26C
SX   Male
AG   61Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=19380521; DOI=10.1093/carcin/bgp097;
RA   Kawaguchi K., Murakami H., Taniguchi T., Fujii M., Kawata S.,
RA   Fukui T., Kondo Y., Osada H., Usami N., Yokoi K., Ueda Y., Yatabe Y.,
RA   Ito M., Horio Y., Hida T., Sekido Y.;
RT   "Combined inhibition of MET and EGFR suppresses proliferation of
RT   malignant mesothelioma cells.";
RL   Carcinogenesis 30:1097-1105(2009).
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RX   PubMed=21245096; DOI=10.1158/0008-5472.CAN-10-2164;
RA   Murakami H., Mizuno T., Taniguchi T., Fujii M., Ishiguro F., Fukui T.,
RA   Akatsuka S., Horio Y., Hida T., Kondo Y., Toyokuni S., Osada H.,
RA   Sekido Y.;
RT   "LATS2 is a tumor suppressor gene of malignant mesothelioma.";
RL   Cancer Res. 71:873-883(2011).
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RX   PubMed=22286761; DOI=10.1038/onc.2012.5;
RA   Mizuno T., Murakami H., Fujii M., Ishiguro F., Tanaka I., Kondo Y.,
RA   Akatsuka S., Toyokuni S., Yokoi K., Osada H., Sekido Y.;
RT   "YAP induces malignant mesothelioma cell proliferation by upregulating
RT   transcription of cell cycle-promoting genes.";
RL   Oncogene 31:5117-5122(2012).
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RX   PubMed=26011428; DOI=10.1111/cas.12698; PMCID=PMC4556387;
RA   Hakiri S., Osada H., Ishiguro F., Murakami H., Murakami-Tonami Y.,
RA   Yokoi K., Sekido Y.;
RT   "Functional differences between wild-type and mutant-type
RT   BRCA1-associated protein 1 tumor suppressor against malignant
RT   mesothelioma cells.";
RL   Cancer Sci. 106:990-999(2015).
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RX   PubMed=28553954; DOI=10.1038/onc.2017.147;
RA   Kato T., Sato T., Yokoi K., Sekido Y.;
RT   "E-cadherin expression is correlated with focal adhesion kinase
RT   inhibitor resistance in merlin-negative malignant mesothelioma
RT   cells.";
RL   Oncogene 36:5522-5531(2017).
//