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Cellosaurus ES-1-OT (CVCL_5122)

[Text version]
Cell line name ES-1-OT
Synonyms ES-10T
Accession CVCL_5122
Resource Identification Initiative To cite this cell line use: ES-1-OT (RRID:CVCL_5122)
Comments Population: Japanese.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr284Glnfs*61 (c.849delC) (p.Arg283fs); Zygosity=Unspecified (PubMed=8221663).
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 10Y
Category Cancer cell line
Publications

PubMed=1792900; DOI=10.1111/j.1442-200X.1991.tb02566.x
Ohta S., Suzuki A., Shimada M., Kosuga M., Taga T., Sugiura Y., Iwai M., Miyahira Y., Okabe H., Suzuki S., Kasahara Y.
Neuronal differentiation of Ewing's sarcoma induced by cholera toxin B and bromodeoxyuridine -- establishment of Ewing's sarcoma cell line and histochemical study.
Acta Paediatr. Jpn. 33:428-433(1991)

PubMed=8221663
Komuro H., Hayashi Y., Kawamura M., Hayashi K., Kaneko Y., Kamoshita S., Hanada R., Yamamoto K., Hongo T., Yamada M., Tsuchida Y.
Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas.
Cancer Res. 53:5284-5288(1993)

PubMed=7591257; DOI=10.1002/ijc.2910630407
Ida K., Kobayashi S., Taki T., Hanada R., Bessho F., Yamamori S., Sugimoto T., Ohki M., Hayashi Y.
EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive neuroectodermal tumor.
Int. J. Cancer 63:500-504(1995)

PubMed=18082704; DOI=10.1016/j.jpedsurg.2007.08.026
Komuro H., Saihara R., Shinya M., Takita J., Kaneko S., Kaneko M., Hayashi Y.
Identification of side population cells (stem-like cell population) in pediatric solid tumor cell lines.
J. Pediatr. Surg. 42:2040-2045(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_5122
IGRhCellID; ES1OT%20GEO
Encyclopedic resources Wikidata; Q54832434
Gene expression databases GEO; GSM393028
Polymorphism and mutation databases Cosmic; 801762
Cosmic; 1078365
Cosmic; 1381109
IARC_TP53; 1271
Progenetix; CVCL_5122
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17