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Cellosaurus SNU-70 (CVCL_5084)

[Text version]
Cell line name SNU-70
Synonyms SNU70
Accession CVCL_5084
Resource Identification Initiative To cite this cell line use: SNU-70 (RRID:CVCL_5084)
Comments Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 118 hours (PubMed=20176655).
Microsatellite instability: Stable (MSS) (PubMed=20176655).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Rectum; UBERON=UBERON_0001052.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1294Ter (c.3880C>T); ClinVar=VCV000469942; Zygosity=Unspecified (PubMed=20176655).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282fs (c.845delG); Zygosity=Homozygous (PubMed=20176655).
Disease Rectal adenocarcinoma (NCIt: C9383)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): KCLB=00070; PubMed=20176655

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133818,19
D3S135815,16
D5S81810,11
D7S8208,11
D8S117912,14
D13S3178,12
D16S53911
D18S5113
D19S43314
D21S1131,32.2
FGA21
TH017,9
TPOX8,9
vWA16,19

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Publications

PubMed=20176655; DOI=10.1093/carcin/bgq043
Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H., Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references
Cell line collections (Providers) KCLB; 00070
Cell line databases/resources cancercelllines; CVCL_5084
ColonAtlas; SNU70
Encyclopedic resources Wikidata; Q54955252
Gene expression databases GEO; GSM1448210
Polymorphism and mutation databases Cosmic; 1322282
IARC_TP53; 28468
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22