Cellosaurus cell line SNU-1544 (CVCL

Cellosaurus SNU-1544 (CVCL_5027)

[Text version]

Cell line name

SNU-1544

Synonyms

SNU1544

Accession

CVCL_5027

Resource Identification Initiative

To cite this cell line use: SNU-1544 (RRID:CVCL_5027)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 42 hours (PubMed=20176655).
Microsatellite instability: Instable (MSI-high) (PubMed=20176655; PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.

Sequence variations

Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Unspecified (PubMed=20176655).
Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (PubMed=20176655).
Mutation; HGNC; HGNC:7127; MLH1; Simple; p.Ser2Leu (c.5C>T); ClinVar=VCV000182533; Zygosity=Unspecified (PubMed=20176655).
Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=20176655).

Disease

Colon adenocarcinoma (NCIt: C4349)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

38Y

Category

Cancer cell line

STR profile

Source(s): DepMap=ACH-001786; KCLB=01544; PubMed=20176655; PubMed=25926053

Markers:

Amelogenin	X
CSF1PO	11,12 (KCLB=01544; PubMed=20176655; PubMed=25926053) 11.1,12 (DepMap=ACH-001786)
D2S1338	19
D3S1358	15,16
D5S818	12
D7S820	11,12
D8S1179	10
D13S317	9,11
D16S539	8,14
D18S51	12,17
D19S433	14.2,16.2
D21S11	29,30
FGA	20,23,24 (DepMap=ACH-001786) 20,24 (PubMed=20176655)
Penta D	8,12
Penta E	9,16
TH01	7,9
TPOX	8
vWA	14,19,20,21 (DepMap=ACH-001786) 14,20 (KCLB=01544; PubMed=20176655) 14,20,21 (PubMed=25926053)

Publications

PubMed=20176655; DOI=10.1093/carcin/bgq043
Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H., Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references

Cell line collections (Providers)

KCLB; 01544

Cell line databases/resources

cancercelllines; CVCL_5027
Cell_Model_Passport; SIDM01838
ColonAtlas; SNU1544
DepMap; ACH-001786

Encyclopedic resources

Wikidata; Q54955119

Gene expression databases

GEO; GSM1448192

Polymorphism and mutation databases

Cosmic; 1322292
IARC_TP53; 28480

Entry history

Entry creation

04-Apr-2012

Last entry update

19-Dec-2024

Version number