| Cell line name |
SNU-1544 |
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| Synonyms |
SNU1544 |
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| Accession |
CVCL_5027 |
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| Resource Identification Initiative |
To cite this cell line use: SNU-1544 (RRID:CVCL_5027) |
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| Comments |
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 42 hours (PubMed=20176655).
Microsatellite instability: Instable (MSI-high) (PubMed=20176655; PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156. |
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| Sequence variations |
- Mutation; HGNC; 583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Unspecified (PubMed=20176655).
- Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (PubMed=20176655).
- Mutation; HGNC; 7127; MLH1; Simple; p.Ser2Leu (c.5C>T); ClinVar=VCV000182533; Zygosity=Unspecified (PubMed=20176655).
- Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=20176655).
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| Disease |
Colon adenocarcinoma (NCIt: C4349) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Female |
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| Age at sampling |
38Y |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): DepMap; KCLB; PubMed=20176655; PubMed=25926053
Markers:| Amelogenin | X |
| CSF1PO | 11,12 (KCLB; PubMed=20176655; PubMed=25926053)
11.1,12 (DepMap) |
| D2S1338 | 19 |
| D3S1358 | 15,16 |
| D5S818 | 12 |
| D7S820 | 11,12 |
| D8S1179 | 10 |
| D13S317 | 9,11 |
| D16S539 | 8,14 |
| D18S51 | 12,17 |
| D19S433 | 14.2,16.2 |
| D21S11 | 29,30 |
| FGA | 20,23,24 (DepMap)
20,24 (PubMed=20176655) |
| Penta D | 8,12 |
| Penta E | 9,16 |
| TH01 | 7,9 |
| TPOX | 8 |
| vWA | 14,19,20,21 (DepMap)
14,20 (KCLB; PubMed=20176655)
14,20,21 (PubMed=25926053) |
Run an STR similarity search on this cell line |
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| Publications | PubMed=20176655; DOI=10.1093/carcin/bgq043
Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H., Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010) PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015) |
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| Cross-references |
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| Cell line collections (Providers) |
KCLB; 01544
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| Cell line databases/resources |
cancercelllines; CVCL_5027
Cell_Model_Passport; SIDM01838
ColonAtlas; SNU1544
DepMap; ACH-001786
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| Encyclopedic resources |
Wikidata; Q54955119
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| Gene expression databases |
GEO; GSM1448192
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| Polymorphism and mutation databases |
Cosmic; 1322292
IARC_TP53; 28480
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| Entry history |
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| Entry creation | 04-Apr-2012 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 23 |
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