Cellosaurus cell line SNU-1181 (CVCL

Cellosaurus SNU-1181 (CVCL_5013)

[Text version]

Cell line name

SNU-1181

Synonyms

SNU1181

Accession

CVCL_5013

Resource Identification Initiative

To cite this cell line use: SNU-1181 (RRID:CVCL_5013)

Comments

Part of: Seoul National University (SNU) cell line collection.
Population: Korean.
Doubling time: 52 hours (PubMed=20176655).
Microsatellite instability: Stable (MSS) (PubMed=20176655; PubMed=25926053).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.

Sequence variations

Mutation; HGNC; HGNC:583; APC; Simple; p.Lys1370Ter (c.4108A>T); Zygosity=Homozygous (PubMed=20176655).
Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Unspecified (PubMed=20176655).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Unspecified (PubMed=20176655).

Disease

Colon adenocarcinoma (NCIt: C4349)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

65Y

Category

Cancer cell line

STR profile

Source(s): KCLB=01181; PubMed=20176655; PubMed=25926053

Markers:

Amelogenin	X
CSF1PO	12
D2S1338	25
D3S1358	16
D5S818	10
D7S820	10,11
D8S1179	10,12
D13S317	10,11
D16S539	10,12
D18S51	17
D19S433	14,15
D21S11	29,32.2
FGA	18,23
TH01	9
TPOX	8
vWA	14,18

Publications

PubMed=20176655; DOI=10.1093/carcin/bgq043
Ku J.-L., Shin Y.-K., Kim D.-W., Kim K.-H., Choi J.-S., Hong S.-H., Jeon Y.-K., Kim S.-H., Kim H.-S., Park J.-H., Kim I.-J., Park J.-G.
Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Carcinogenesis 31:1003-1009(2010)

PubMed=25926053; DOI=10.1038/ncomms8002
Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Nat. Commun. 6:7002.1-7002.10(2015)

Cross-references

Cell line collections (Providers)

KCLB; 01181

Cell line databases/resources

cancercelllines; CVCL_5013
ColonAtlas; SNU1181

Encyclopedic resources

Wikidata; Q54955102

Gene expression databases

GEO; GSM1448219

Polymorphism and mutation databases

Cosmic; 1322287
IARC_TP53; 28473

Entry history

Entry creation

04-Apr-2012

Last entry update

19-Dec-2024

Version number