ID   TC-4C
AC   CVCL_4Z37
DR   cancercelllines; CVCL_4Z37
DR   Cosmic; 2228245
DR   Wikidata; Q54971814
RX   PubMed=25010205;
CC   Sequence variation: Gene fusion; HGNC; HGNC:3446; ERG + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ERG, EWS-ERG (PubMed=25010205).
CC   Sequence variation: Mutation; HGNC; HGNC:11355; STAG2; Unexplicit; Ex5-12del; Zygosity=Hemizygous (PubMed=25010205).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu194Arg (c.581T>G); ClinVar=VCV000376633; Zygosity=Unspecified (PubMed=25010205).
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): PubMed=25010205
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 13
ST   D16S539: 9,11
ST   D18S51: 12,17
ST   D19S433: 14,16.2
ST   D21S11: 29
ST   D2S1338: 19,26
ST   D3S1358: 16
ST   D5S818: 10
ST   D7S820: 11
ST   D8S1179: 12
ST   FGA: 20,22
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 15,18
DI   NCIt; C27291; Ewing sarcoma/peripheral primitive neuroectodermal tumor
DI   ORDO; Orphanet_223727; Bone sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 14-12-15; Last updated: 19-12-24; Version: 12
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RX   PubMed=25010205; DOI=10.1371/journal.pgen.1004475; PMCID=PMC4091782;
RA   Brohl A.S., Solomon D.A., Chang W., Wang J.-J., Song Y., Sindiri S.,
RA   Patidar R., Hurd L., Chen L., Shern J.F., Liao H.-L., Wen X.-Y.,
RA   Gerard J., Kim J.-S., Lopez Guerrero J.A., Machado I., Wai D.H.,
RA   Picci P., Triche T.J., Horvai A.E., Miettinen M.M., Wei J.S.,
RA   Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.;
RT   "The genomic landscape of the Ewing sarcoma family of tumors reveals
RT   recurrent STAG2 mutation.";
RL   PLoS Genet. 10:E1004475-E1004475(2014).
//