Cellosaurus cell line TC-215 (CVCL

Cellosaurus TC-215 (CVCL_4Z32)

[Text version]

Cell line name

TC-215

Accession

CVCL_4Z32

Resource Identification Initiative

To cite this cell line use: TC-215 (RRID:CVCL_4Z32)

Comments

Omics: Transcriptome analysis by RNAseq.

Sequence variations

Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 2 fusion (Ex7/Ex5) (PubMed=25010205).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Cys (c.377A>G); ClinVar=VCV000458541; Zygosity=Unspecified (PubMed=25010205).

Disease

Ewing sarcoma/peripheral primitive neuroectodermal tumor (NCIt: C27291)
Bone sarcoma (ORDO: Orphanet_223727)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Category

Cancer cell line

STR profile

Source(s): PubMed=25010205

Markers:

Amelogenin	X,Y
CSF1PO	11,12
D2S1338	16,26
D3S1358	14,17
D5S818	12,13
D7S820	8,10
D8S1179	12,16
D13S317	12
D16S539	12
D18S51	14,16
D19S433	14
D21S11	28,34.2
FGA	19,22
TH01	6,9.3
TPOX	8,9
vWA	16,18

Publications

PubMed=25010205; DOI=10.1371/journal.pgen.1004475; PMCID=PMC4091782
Brohl A.S., Solomon D.A., Chang W., Wang J.-J., Song Y., Sindiri S., Patidar R., Hurd L., Chen L., Shern J.F., Liao H.-L., Wen X.-Y., Gerard J., Kim J.-S., Lopez Guerrero J.A., Machado I., Wai D.H., Picci P., Triche T.J., Horvai A.E., Miettinen M.M., Wei J.S., Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.
The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation.
PLoS Genet. 10:E1004475-E1004475(2014)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_4Z32

Encyclopedic resources

Wikidata; Q54971800

Polymorphism and mutation databases

Cosmic; 2228238

Entry history

Entry creation

14-Dec-2015

Last entry update

19-Dec-2024

Version number