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Cellosaurus TC-205 (CVCL_4Z31)

[Text version]
Cell line name TC-205
Synonyms TC205
Accession CVCL_4Z31
Resource Identification Initiative To cite this cell line use: TC-205 (RRID:CVCL_4Z31)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Deep exome analysis.
Sequence variations
  • Gene fusion; HGNC; 3508; EWSR1 + HGNC; 18562; FEV; Name(s)=EWSR1-FEV, EWS-FEV; Note=EWSR1 exon 7 fused to FEV exon 3 (DOI=10.5282/edoc.27750).
Disease Ewing sarcoma/peripheral primitive neuroectodermal tumor (NCIt: C27291)
Bone sarcoma (ORDO: Orphanet_223727)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): PubMed=25010205

Markers:
AmelogeninX
CSF1PO10
D2S133817,25
D3S135817
D5S81812
D7S82010,12
D8S117912,13
D13S3178,10
D16S53913
D18S5115
D19S43314,17.2
D21S1128,30
FGA21,23
TH018,9
TPOX8,11
vWA15,16

Run an STR similarity search on this cell line
Web pages https://www.cccells.org/tables/Ewings.php
Publications

PubMed=25010205; DOI=10.1371/journal.pgen.1004475
Brohl A.S., Solomon D.A., Chang W., Wang J.-J., Song Y., Sindiri S., Patidar R., Hurd L., Chen L., Shern J.F., Liao H.-L., Wen X.-Y., Gerard J., Kim J.-S., Lopez Guerrero J.A., Machado I., Wai D.H., Picci P., Triche T.J., Horvai A.E., Miettinen M.M., Wei J.S., Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.
The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation.
PLoS Genet. 10:E1004475-E1004475(2014)

DOI=10.5282/edoc.27750
Orth M.F.
Systematic multi-omics profiling of Ewing sarcoma cell lines.
Thesis PhD (2021), Ludwig Maximilians University of Munich, Germany

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01466
DepMap; ACH-001431
Encyclopedic resources Wikidata; Q54971797
Polymorphism and mutation databases Cosmic; 2228237
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number9