Cellosaurus cell line TC-205 (CVCL

Cellosaurus TC-205 (CVCL_4Z31)

[Text version]

Cell line name

TC-205

Synonyms

TC205

Accession

CVCL_4Z31

Resource Identification Initiative

To cite this cell line use: TC-205 (RRID:CVCL_4Z31)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Deep exome analysis.

Sequence variations

Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:18562; FEV; Name(s)=EWSR1-FEV, EWS-FEV; Note=EWSR1 exon 7 fused to FEV exon 3 (DOI=10.5282/edoc.27750).

Disease

Ewing sarcoma/peripheral primitive neuroectodermal tumor (NCIt: C27291)
Bone sarcoma (ORDO: Orphanet_223727)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Category

Cancer cell line

STR profile

Source(s): PubMed=25010205

Markers:

Amelogenin	X
CSF1PO	10
D2S1338	17,25
D3S1358	17
D5S818	12
D7S820	10,12
D8S1179	12,13
D13S317	8,10
D16S539	13
D18S51	15
D19S433	14,17.2
D21S11	28,30
FGA	21,23
TH01	8,9
TPOX	8,11
vWA	15,16

Web pages

https://www.cccells.org/tables/Ewings.php

Publications

PubMed=25010205; DOI=10.1371/journal.pgen.1004475; PMCID=PMC4091782
Brohl A.S., Solomon D.A., Chang W., Wang J.-J., Song Y., Sindiri S., Patidar R., Hurd L., Chen L., Shern J.F., Liao H.-L., Wen X.-Y., Gerard J., Kim J.-S., Lopez Guerrero J.A., Machado I., Wai D.H., Picci P., Triche T.J., Horvai A.E., Miettinen M.M., Wei J.S., Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.
The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation.
PLoS Genet. 10:E1004475-E1004475(2014)

DOI=10.5282/edoc.27750
Orth M.F.
Systematic multi-omics profiling of Ewing sarcoma cell lines.
Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany

Cross-references

Cell line databases/resources

Cell_Model_Passport; SIDM01466
DepMap; ACH-001431

Encyclopedic resources

Wikidata; Q54971797

Polymorphism and mutation databases

Cosmic; 2228237

Entry history

Entry creation

14-Dec-2015

Last entry update

19-Dec-2024

Version number